Dogs susceptibility to rabies after a vaccination campaign in endemic areas of Perú

Authors

  • Ricardo López I Laboratorio de Referencia Nacional de Rabia, Centro Nacional de Salud Pública, Instituto Nacional de Salud. Lima, Perú. Médico Veterinario.
  • Albina Díaz O Laboratorio de Referencia Nacional de Rabia, Centro Nacional de Salud Pública, Instituto Nacional de Salud. Lima, Perú. Biólogo.
  • Edgar Condori C Laboratorio de Referencia Nacional de Rabia, Centro Nacional de Salud Pública, Instituto Nacional de Salud. Lima, Perú. Biólogo.

DOI:

https://doi.org/10.17843/rpmesp.2007.241.1079

Keywords:

Dog rabies, Rabies vaccines, Vaccination /veterinary, Serologic survey

Abstract

Objective:To determine the level of immune response after a mass vaccination campaign against rabies in two areas which presented cases of canine rabies in the last years. Materials and methods: A serologic survey was carried out in 101 and 199 dogs located respectively, in the cities of Tambo Grande (Piura) and Juliaca (Puno) and a rabies serum mouse neutralization test was perform to measure neutralizing antibodies (≥ 0,5 UI/mL) according to area of study, vaccination antecedents, age and sex of the dog. Results: After three months of the rabies campaign 32% of all dogs were properly protected, 66% had vaccination antecedents and only 44% of the vaccinated dogs had antibodies (> 0,1 UI/mL). A greater protection against rabies was found in Juliaca than in Tambo Grande in vaccinated dogs (51 vs 34%, p<0,05). Dogs older than a year old were better protected than dogs under a year old (p<0,01), but non relation was found between sex and protection (p>0,05). Conclusions: This study found that there is a poor immune response against rabies in the districts of Tambo Grande, and Juliaca, making them very susceptible to develop dog rabies outbreak.

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Published

2007-03-18

Issue

Section

Research Articles

How to Cite

1.
López I R, Díaz O A, Condori C E. Dogs susceptibility to rabies after a vaccination campaign in endemic areas of Perú. Rev Peru Med Exp Salud Publica [Internet]. 2007 Mar. 18 [cited 2024 Nov. 21];24(1). Available from: https://rpmesp.ins.gob.pe/index.php/rpmesp/article/view/1079