Invasive pneumococcal disease in patients from a pediatric hospital in Peru, 2017-2020

Authors

DOI:

https://doi.org/10.17843/rpmesp.2022.394.12054

Keywords:

Streptococcus pneumoniae, Pneumococcal Vaccines, Child, Hyperuricemia

Abstract

This study aimed to describe the clinical characteristics, serotypes, and antibiotic susceptibility in patients with invasive pneumococcal disease (IPD). The medical records of patients with IPD who were hospitalized at the Instituto Nacional de Salud del Niño-Breña (Lima, Peru) were reviewed. We evaluated 29 patients. The median age was 1.9 years (interquartile range: 1 to 4 years). Of the sample, 51.7% were women and the most frequent clinical form of IPD was bacteremia in 18 (62.1%) patients; 65.5% had a complete vaccination schedule, according to the Peruvian Ministry of Health. Germ isolation was performed from blood samples in 82.8% of patients. Antibiotic resistance to erythromycin (55.2%) was the most frequent, followed by
resistance to trimethoprim-sulfamethoxazole (48.3%) and penicillin (24.1%). The isolated serotypes were 6C, 19A, 23A and 24F. One patient died of meningitis. In conclusion, IPD was more frequent in children aged one to five years and the most frequent clinical form was bacteremia. Five serotypes reported in previous studies were found to be resistant to penicillin and erythromycin.

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References

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Published

2022-12-19

Issue

Section

Brief Report

How to Cite

1.
Marín-Portocarrero JG, Quispe-Sanchez A, Charca-Rodriguez F de M, Atamari-Anahui N. Invasive pneumococcal disease in patients from a pediatric hospital in Peru, 2017-2020. Rev Peru Med Exp Salud Publica [Internet]. 2022 Dec. 19 [cited 2024 Jun. 19];39(4):469-73. Available from: https://rpmesp.ins.gob.pe/index.php/rpmesp/article/view/12054

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