Genotoxic effect of potassium dicromate in peripheral blood erythrocytes of Oreochromis niloticus (tilapia)

Authors

  • Zulita Prieto Laboratorio de Genética, Facultad de Ciencias Biológicas, Universidad Nacional de Trujillo. Trujillo, Perú. Biólogo.
  • Julio León-Incio Laboratorio de Genética, Facultad de Ciencias Biológicas, Universidad Nacional de Trujillo. Trujillo, Perú. Biólogo.
  • Carlos Quijano-Jara Laboratorio de Genética, Facultad de Ciencias Biológicas, Universidad Nacional de Trujillo. Trujillo, Perú. Biólogo.
  • Radigud Fernández Laboratorio de Genética, Facultad de Ciencias Biológicas, Universidad Nacional de Trujillo. Trujillo, Perú. Biólogo.
  • Edgardo Polo-Benites Laboratorio de Genética, Facultad de Ciencias Biológicas, Universidad Nacional de Trujillo. Trujillo, Perú. Biólogo.
  • Roger Vallejo-Rodriguez Laboratorio de Genética, Facultad de Ciencias Biológicas, Universidad Nacional de Trujillo. Trujillo, Perú. Estudiante de biología.
  • Luis Villegas-Sánchez Laboratorio de Genética, Facultad de Ciencias Biológicas, Universidad Nacional de Trujillo. Trujillo, Perú. Estudiante de biología.

DOI:

https://doi.org/10.17843/rpmesp.2008.251.1236

Keywords:

Genotoxicity, Chromium, Potassium dichromate, Biological models, Micronucleus test

Abstract

Due multiple reports of the genotoxic and carcinogenic effect of chromium VI and the permanent exposure of the human beings to this element. Objective. Contributing new evidence of the genotoxicity of potassium dichromate using the biological system Oreochromis niloticus “tilapia” through the micronucleus test and the nuclear quantification of buds in erythrocytes of peripheral blood. Material and methods. The individuals were exposed to increasing concentrations (0.0, 0.2, 0.4 and 0.8 ppm) of potassium dichromate. Peripheral blood samples of the branchial arc of each individual were taken at 3th and 7th day of treatment which were processed and colored with Giemsa 5%, erythrocytes in peripheral blood with micronuclei and nuclear buds were quantified. Results. A significant increase of frequencies of micronucleus and nuclear buds in the exposed individuals were registered which were directly proportional to the potassium dichromate concentration (p<0.05). Conclusions. Potassium dichromate caused genetic damage in the cells of O. niloticus.

Downloads

Download data is not yet available.

Downloads

Published

2008-03-31

Issue

Section

Research Articles

How to Cite

1.
Prieto Z, León-Incio J, Quijano-Jara C, Fernández R, Polo-Benites E, Vallejo-Rodriguez R, et al. Genotoxic effect of potassium dicromate in peripheral blood erythrocytes of Oreochromis niloticus (tilapia). Rev Peru Med Exp Salud Publica [Internet]. 2008 Mar. 31 [cited 2024 Jun. 23];25(1). Available from: https://rpmesp.ins.gob.pe/index.php/rpmesp/article/view/1236

Most read articles by the same author(s)