Characteristics of hemolytic uremic syndrome in patients from a pediatric hospital in Peru, 2010-2020

Authors

  • Lisbeth Varenia Carrasco-Oros Instituto Nacional de Salud del Niño-Breña, Lima, Perú. Facultad de Medicina Humana, Universidad Nacional Mayor de San Marcos, Lima, Perú. https://orcid.org/0000-0003-3926-3310
  • Noé Atamari-Anahui Instituto Nacional de Salud del Niño-Breña, Lima, Perú. Unidad de Investigación para la Generación y Síntesis de Evidencias en Salud, Vicerrectorado de Investigación, Universidad San Ignacio de Loyola, Lima, Perú. https://orcid.org/0000-0001-8283-6669
  • Alcida Goñi-Fano Instituto Nacional de Salud del Niño-Breña, Lima, Perú. Facultad de Medicina Humana, Universidad Nacional Mayor de San Marcos, Lima, Perú. https://orcid.org/0000-0003-2584-5547
  • Claudia Sosa-Carmelo Instituto Nacional de Salud del Niño-Breña, Lima, Perú. Facultad de Medicina Humana, Universidad Nacional Mayor de San Marcos, Lima, Perú.
  • Eduardo Jesús Guzmán-Quispe Instituto Nacional de Salud del Niño-Breña, Lima, Perú. https://orcid.org/0000-0002-3494-8751
  • Nadin Conto-Palomino Facultad de Medicina Humana, Universidad Nacional Mayor de San Marcos, Lima, Perú. Servicio de pediatría, Hospital Nacional Arzobispo Loayza, Lima, Perú. https://orcid.org/0000-0002-3584-0806
  • Basem Rodolfo Cabrera-Villacriz Instituto Nacional de Salud del Niño-Breña, Lima, Perú. https://orcid.org/0000-0001-7182-9420
  • Carla Lisette Apeña-Cabrera Instituto Nacional de Salud del Niño-Breña, Lima, Perú. https://orcid.org/0009-0003-4642-7309

DOI:

https://doi.org/10.17843/rpmesp.2023.402.12708

Keywords:

Hemolytic uremic syndrome, Renal Replacement Therapy, Child, Peru

Abstract

This study aimed to describe the clinical-epidemiological, laboratory, treatment, and follow-up characteristics of patients with hemolytic uremic syndrome (HUS). The medical records of patients with HUS hospitalized at the Instituto Nacional de Salud del Niño-Breña (INSN-B) (Lima, Peru) were reviewed. We evaluated 83 patients. The median age was 22 months (interquartile range: 14 to 30 months). Of the sample, 71.1% (59) registered previous use of antibiotics. Seventy-two (86.8%) had oligoanuria and 62
(74.6%) had diarrhea. Five cultures were positive (two enterohaemorrhagic Escherichia coli). Forty-nine (59%) required renal replacement therapy. No patient died during hospitalization. At one year of follow-up, seven patients developed post-HUS nephropathy. In conclusion, in INSN-B, the median age was like previous years and there was a higher frequency of oligoanuria, and renal replacement therapy compared to previous reports.

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References

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Published

2023-06-26

Issue

Section

Brief Report

How to Cite

1.
Carrasco-Oros LV, Atamari-Anahui N, Goñi-Fano A, Sosa-Carmelo C, Guzmán-Quispe EJ, Conto-Palomino N, et al. Characteristics of hemolytic uremic syndrome in patients from a pediatric hospital in Peru, 2010-2020. Rev Peru Med Exp Salud Publica [Internet]. 2023 Jun. 26 [cited 2024 Dec. 3];40(2):207-12. Available from: https://rpmesp.ins.gob.pe/index.php/rpmesp/article/view/12708

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