First report of an acute case of Chagas disease in the municipality of Miraflores, Guaviare, Colombia

José Ziadé Benítez; Diana Cedeño Díaz; Luz Alba Colorado; Laureano Mosquera Murillo; María Trinidad Orozco; Sandra Vallecilla; Julio Cesar Padilla; Mario J. Olivera

doi:10.17843/rpmesp.2024.412.13271

Authors

José Ziadé Benítez Programa Departamental Enfermedades Transmitidas por Vectores y Zoonosis, Secretaría de Salud del Guaviare, Guaviare, Colombia https://orcid.org/0009-0006-7826-1712
Diana Cedeño Díaz Laboratorio Departamental de Salud Pública, Secretaría de Salud del Guaviare, Guaviare, Colombia https://orcid.org/0009-0002-4615-4243
Luz Alba Colorado Área de Vigilancia en Salud Pública, Secretaría de Salud del Guaviare, Guaviare, Colombia https://orcid.org/0009-0005-4995-4002
Laureano Mosquera Murillo Departamento de Entomología, Laboratorio Departamental de Salud Pública, Secretaría de Salud del Guaviare, Guaviare, Colombia https://orcid.org/0000-0001-8304-7530
María Trinidad Orozco Área de Vigilancia en Salud Pública, Secretaría de Salud del Guaviare, Guaviare, Colombia https://orcid.org/0000-0001-5498-0970
Sandra Vallecilla Área de Vigilancia en Salud Pública, Secretaría de Salud de Miraflores, Guaviare, Colombia https://orcid.org/0009-0005-5166-7467
Julio Cesar Padilla Red de Gestión de Conocimiento, Investigación e Innovación en Malaria, Bogotá, Colombia https://orcid.org/0000-0001-7608-9863
Mario J. Olivera Grupo de Parasitología, Instituto Nacional de Salud de Colombia, Bogotá, Colombia https://orcid.org/0000-0002-6885-6353

DOI:

https://doi.org/10.17843/rpmesp.2024.412.13271

Keywords:

Benznidazole, Case Reports, Chagas disease, Nifurtimox, Trypanosoma cruzi

Abstract

We present a case of acute phase Chagas disease in a 40-year-old male patient from Vereda Buenos Aires, Municipality of Miraflores, Department of Guaviare. The patient attended the emergency department with fever, headache, asthenia, adynamia and dysuria. The blood smear and urinalysis were positive for symptomatic urinary tract infection, but negative for malaria. Five days later the diagnosis of acute phase Chagas disease was confirmed after a positive result for Trypanosoma cruzi. The patient was treated with nifurtimox and benznidazole, his contacts and risk areas were investigated, an active entomological community and institutional search was carried out, as well as in the reservoirs, finally, laboratory surveillance for possible cases of infection in the community was conducted. Five cases with similar symptoms were identified, but parasitological tests were negative. Health education measures were implemented to prevent the spread of the disease.

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