Evaluation of two immunoblot tests with goat and sheep hydatid antigen for human echinococcosis diagnosis
DOI:
https://doi.org/10.17843/rpmesp.2010.272.1466Keywords:
Echinococcosis, Blotting, western, Sensitivity and specificity, Cross-primingAbstract
To estimate the diagnosis value of goat and ovine antigen for echinococcosis immunoblot test, 135 serums were used, of which 70 were coming from patients with hydatid disease confirmed by the finding of proto scolex and membrane in the pathology study of surgical piece, 45 from patients with other parasitic diseases and 20 apparently healthy people. The sensitivity, the specificity, positive and negative predictive value of immunoblot test, with hidatyd antigen of goat was of 92.8%, 100%, 100%, 92.8%, respectively, than for ovine antigen was 91.4%, 95.3%, 95.5%, 91.1%, respectively. Kappa index was 0.93 for goat antigen and 0.86 with sheep in relation to the pathological study. We recommended the use of both antigens for the serologic diagnosis of human echinococcosis.Downloads
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Published
2010-06-25
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Section
Research Articles
How to Cite
1.
Miranda E, Velarde F, Somocurcio J, Ayala E. Evaluation of two immunoblot tests with goat and sheep hydatid antigen for human echinococcosis diagnosis. Rev Peru Med Exp Salud Publica [Internet]. 2010 Jun. 25 [cited 2024 Nov. 4];27(2). Available from: https://rpmesp.ins.gob.pe/index.php/rpmesp/article/view/1466