Need for standardization in norepinephrine dosage in the management of septic shock

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DOI:

https://doi.org/10.17843/rpmesp.2025.424.15450

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References

Evans L, Rhodes A, Alhazzani W, Antonelli M, Coopersmith CM, French C, et al. Surviving sepsis campaign: international guidelines for management of sepsis and septic shock 2021. Intensive Care Med. 2021;47(11):1181-1247. doi: 10.1007/s00134-021-06506-y.

Morales S, Wendel-Garcia PD, Ibarra-Estrada M, Jung C, Castro R, Retamal J, et al. The impact of norepinephrine dose reporting heterogeneity on mortality prediction in septic shock patients. Crit Care. 2024;28(1):216. doi: 10.1186/s13054-024-05011-0.

Leone M, Goyer I, Levy B, Dünser MW, Asfar P, Jentzer JC. Dose of norepinephrine: the devil is in the details. Intensive Care Med.

;48(5):638-640. doi: 10.1007/s00134-022-06652-x.

Goyer I, Levy B, Leone M. Norepinephrine dose and concentration reporting: a closer look at the fine print. Intensive Care Med. 2024;50(6):1006-1007. doi: 10.1007/s00134-024-07425-4.

Kattan E, Ibarra-Estrada M, Jung C. Norepinephrine dose and concentration reporting: the devil is in the details. Intensive Care Med.

;50(6):1008-1009. doi: 10.1007/s00134-024-07446-z.

Wieruszewski PM. Norepinephrine dosage: the details go beyond a grain of salt. Intensive Care Med. 2023;49(6):714-715. doi:

1007/s00134-023-07077-w.

Published

2025-12-11

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Section

Letters to the Editor

How to Cite

1.
Cerna J, Aliaga L, Amado J, Torres D, Martínez P, Lisson R, et al. Need for standardization in norepinephrine dosage in the management of septic shock. Rev Peru Med Exp Salud Publica [Internet]. 2025 Dec. 11 [cited 2026 Jun. 11];42(4):458-9. Available from: https://rpmesp.ins.gob.pe/index.php/rpmesp/article/view/15450