Protector effect of Helianthus annuus (Sunflower) on myocardial infarction in New Zealand rabbit

Authors

  • Edith Guardia-Espinoza Facultad de Medicina. Universidad Nacional Mayor de San Marcos. Lima, Peru. Asociación para el Desarrollo de la Investigacion en Ciencias de la Salud. Lima, Peru.
  • Gianina Liseth del Carmen Herrera-Hurtado Facultad de Medicina. Universidad Nacional Mayor de San Marcos. Lima, Peru. Asociacion para el Desarrollo de la Investigacion en Ciencias de la Salud. Lima, Peru.
  • Saúl Garrido-Jacobi Facultad de Medicina. Universidad Nacional Mayor de San Marcos. Lima, Peru.
  • Danitza Cárdenas-Peralta Facultad de Medicina. Universidad Nacional Mayor de San Marcos. Lima, Peru. Asociacion para el Desarrollo de la Investigacion en Ciencias de la Salud. Lima, Peru.
  • Christian Martínez-Romero Facultad de Medicina. Universidad Nacional Mayor de San Marcos. Lima, Peru.
  • Pedro Hernández-Figueroa Facultad de Medicina. Universidad Nacional Mayor de San Marcos. Lima, Peru.
  • Mary Condori-Calizaya Facultad de Medicina. Universidad Nacional Mayor de San Marcos. Lima, Peru.
  • Juan La Barrera-Llacchua Facultad de Medicina. Universidad Nacional Mayor de San Marcos. Lima, Peru.
  • Miguel Flores-Ángeles Facultad de Medicina. Universidad Nacional Mayor de San Marcos. Lima, Peru.

DOI:

https://doi.org/10.17843/rpmesp.2015.321.1578

Keywords:

Myocardial infarction, Helianthus annuus, Epinephrine

Abstract

Objectives. Determine the protective effect of oil Helianthus annuus (Sunflower) on myocardial infarction induced by epinephrine in New Zealand rabbits. Materials and methods. The rabbits were randomized into five groups (8 per group): blank, negative control, experimental 1 (10 mg / kg), experimental 2 (20 mg / kg) and three experimental (40 mg/ kg). Experimental groups 1, 2 and 3 received Helianthus annuus oil for two weeks. Epinephrine (2 mg/Kg) to the negative, Experimental Control 1, 2 and 3 groups was given over two consecutive days with an interval of 24 h after pretreatment with oil. Twenty four hours after the last administration, the rabbits were anesthetized and sacrificed. Serum troponin I and polymorphonuclear evaluated by .mu.m.sup.2. Results. Significant difference between the negative control group and the experimental groups 1, 2 and 3 was found in the serum variables troponin I and polymorphonuclear by .mu.m.sup.2. Conclusions. Helianthus annuus oil at doses of 20 mg/kg has protective effect on myocardial infarction induced by epinephrine in New Zealand rabbits.

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Published

2015-04-01

Issue

Section

Research Articles

How to Cite

1.
Guardia-Espinoza E, Herrera-Hurtado GL del C, Garrido-Jacobi S, Cárdenas-Peralta D, Martínez-Romero C, Hernández-Figueroa P, et al. Protector effect of Helianthus annuus (Sunflower) on myocardial infarction in New Zealand rabbit. Rev Peru Med Exp Salud Publica [Internet]. 2015 Apr. 1 [cited 2024 Jun. 23];32(1):80-6. Available from: https://rpmesp.ins.gob.pe/index.php/rpmesp/article/view/1578

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