Rabdomiolisis y miopatía como únicas manifestaciones de hipotiroidismo severo secundario a tiroiditis de Hashimoto

Juan P. Brito; Juan P. Domecq; Gabriela Prutsky; Germán Málaga; Larry Young; Atil Y. Kargi

doi:10.17843/rpmesp.2013.301.170

Authors

Juan P. Brito Division of Endocrinology, Diabetes, Metabolism, and Nutrition, Mayo Clinic. Rochester, EE. UU. Knowledge and Evaluation Research Unit, Mayo Clinic. Rochester, EE. UU. Médico endocrinólogo.
Juan P. Domecq Knowledge and Evaluation Research Unit, Mayo Clinic. Rochester, EE. UU. Unidad de Conocimiento y Evidencia, Universidad Peruana Cayetano Heredia. Lima, Perú. médico cirujano.
Gabriela Prutsky Knowledge and Evaluation Research Unit, Mayo Clinic. Rochester, EE. UU. Unidad de Conocimiento y Evidencia, Universidad Peruana Cayetano Heredia. Lima, Perú. médico cirujano.
Germán Málaga Knowledge and Evaluation Research Unit, Mayo Clinic. Rochester, EE. UU. Unidad de Conocimiento y Evidencia, Universidad Peruana Cayetano Heredia. Lima, Perú. médico internista.
Larry Young Department of Rheumatology, Miami Veterans Affairs Medical Center. Miami, EE. UU. médico reumatólogo.
Atil Y. Kargi Department of Endocrinology, University of Miami/Jackson Memorial Hospital. Miami, EE. UU. Médico endocrinólogo.

DOI:

https://doi.org/10.17843/rpmesp.2013.301.170

Keywords:

Hypothyroidism, Muscular Diseases, Rhabdomyolysis, Thyroiditis, Neuromuscular diseases, Neuromuscular manifestations

Abstract

Hashimoto’s thyroiditis is the most frequent cause of hypothyroidism. In the regions with no iodine deficiency, it is more frequent in women and oftentimes has a familial association. The symptoms and signs of hypothyroidism are systemic and depend on the duration and intensity of the thyroid hormone deficiency. Neuromuscular manifestations are seldom the only symptoms and signs present. We present the case of a young patient with severe myopathy, where rhabdomyolysis was the sole manifestation of severe hypothyroidism secondary to Hashimoto’s thyroiditis.