Antimicrobial resistance of Bartonella bacilliformis strains from regions endemic to bartonellosis in Peru

Authors

  • Giovanna Mendoza-Mujica Laboratorio de Metaxenicas Bacterianas, Area Bartonelosis. Centro Nacional de Salud Publica. Instituto Nacional de Salud. Lima, Peru.
  • Diana Flores-León Laboratorio de Metaxenicas Bacterianas, Area Bartonelosis. Centro Nacional de Salud Publica. Instituto Nacional de Salud. Lima, Peru.

DOI:

https://doi.org/10.17843/rpmesp.2015.324.1755

Keywords:

Bartonella bacilliformis, Ciprofloxacin, Chloramphenicol, Disk diffusion antimicrobial tests, Agar dilution count

Abstract

Objectives. To evaluate in vitro antimicrobial susceptibility to chloramphenicol (CHL) and ciprofloxacin (CIP) in strains of Bartonella bacilliformis from areas that are endemic to Bartonellosis in Peru, through three laboratory methods. Materials and methods. Antimicrobial susceptibility to CHL and CIP from 100 strains of Bartonella bacilliformis isolated in patients
from the regions of Ancash, Cusco, Cajamarca, Lima and La Libertad were evaluated. Strains were evaluated by: disk diffusion, E-test and agar dilution. Results. 26% of the strains of Bartonella bacilliformis evaluated were resistant to CIP and 1% to CHL. Similar patterns of antimicrobial sensitivity / resistance were obtained in all three methods. Conclusions. Bartonella bacilliformis strains circulating in Peru have high levels of in vitro resistance to CIP, so it is advisable to expand research on the use of drug treatment regimens of the Bartonellosis. The methods of E-test and disk diffusion were the most suitable for assessment in vitro of antimicrobial susceptibility of the microorganism.

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Published

2015-12-05

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Original Article

How to Cite

1.
Mendoza-Mujica G, Flores-León D. Antimicrobial resistance of Bartonella bacilliformis strains from regions endemic to bartonellosis in Peru. Rev Peru Med Exp Salud Publica [Internet]. 2015 Dec. 5 [cited 2024 Apr. 23];32(4):659-66. Available from: https://rpmesp.ins.gob.pe/index.php/rpmesp/article/view/1755

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