Markers of plasmid resistance to qnr quinolones in clinical isolates of CTX-M beta-lactamases-producing enterobacteria in Lima, Peru

Authors

  • Lesdyth Jessica Toribio Arias Escuela de Tecnología Médica, Universidad Nacional Mayor de San Marcos. Lima, Perú. Tecnólogo médico
  • Carlos Raúl Sevilla Andrade Escuela de Tecnología Médica, Universidad Nacional Mayor de San Marcos. Lima, Perú. Centro de Investigaciones Tecnológicas, Biomédicas y Medioambientales - CITBM, Universidad Nacional Mayor de San Marcos. Lima, Perú. magíster en Microbiología
  • Edgar Gonzales-Escalante Centro de Investigaciones Tecnológicas, Biomédicas y Medioambientales - CITBM, Universidad Nacional Mayor de San Marcos. Lima, Perú. Instituto Nacional de Salud del Niño. Lima, Perú. Tecnólogo médico, magíster en Microbiología

DOI:

https://doi.org/10.17843/rpmesp.2019.362.3960

Keywords:

Bacterial drug resistance, Quinolones, Beta-lactamases, Enterobacteriaceae

Abstract

Aimed at reporting markers of plasmid resistance to qnr quinolones in clinical isolates of CTX-M beta-lactamase-producing enterobacteria, a descriptive study was conducted with isolates from the strain repository of TO-06/09 project of the National Children´s Health Institute. 138 isolates were recovered. Antimicrobial susceptibility was determined by the diffusion disk method, and gene identification by polymerase chain reaction. Of the 138 isolates, 67 (48.5%) were genotypically positive for qnr proteins; of these, 38 (56.7%) had qnrB determinants and 48 (71.6%) had qnrS determinants. No isolate presented qnrA determinants. qnr determinants were detected in isolates containing CTX-M beta-lactamases in a non-exposed population.

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Published

2019-06-28

Issue

Section

Brief Report

How to Cite

1.
Toribio Arias LJ, Sevilla Andrade CR, Gonzales-Escalante E. Markers of plasmid resistance to qnr quinolones in clinical isolates of CTX-M beta-lactamases-producing enterobacteria in Lima, Peru. Rev Peru Med Exp Salud Publica [Internet]. 2019 Jun. 28 [cited 2024 Apr. 21];36(2):265-9. Available from: https://rpmesp.ins.gob.pe/index.php/rpmesp/article/view/3960

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