Specificity of the intradermal montenegro test in patients infected by trypanosoma cruzi from different regions of Peru
DOI:
https://doi.org/10.17843/rpmesp.2014.312.46Keywords:
Chagas disease, Leishmaniosis, Diagnosis, Hypersensitivity, delayedAbstract
In order to assess the specificity of the leishmanin skin test in Chagas disease patients without clinical history of leishmaniasis, present or former. A sample of 102 persons infected with Trypanosoma cruzi (14 acute cases with parasitological diagnosis and 88 chronic cases) through the demonstration of IgG antibodies by ELISA and indirect immunofluorescence (IIF) were evaluated with leishmanin soluble antigen which contained Leishmania (Viannia) peruviana concentration of 25-30 ug/mL. Only five people showed cutaneous hypersensitivity reaction to the application of the antigen between hours 48 and 72. The Leishmanin skin test evaluated was negative in 97 people infected with T. cruzi, thus specificity of 95.1% was achieved. In conclusion, the intradermal Montenegro test is a simple and effective diagnostic tool that also could be used to discriminate infections by Leishmania or T. cruzi, in Peruvian geographic areas where both parasites are present.Downloads
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Published
2014-07-02
Issue
Section
Research Articles
How to Cite
1.
Minaya-Gómez G, Vargas-Apaza S, Monteza-Zuloeta Y, Purisaca-Morante E, Delgado-Diaz F. Specificity of the intradermal montenegro test in patients infected by trypanosoma cruzi from different regions of Peru. Rev Peru Med Exp Salud Publica [Internet]. 2014 Jul. 2 [cited 2024 Dec. 10];31(2). Available from: https://rpmesp.ins.gob.pe/index.php/rpmesp/article/view/46