COVID-19–associated multisystem inflammatory syndrome in children: case series at a pediatric hospital in Peru

Authors

DOI:

https://doi.org/10.17843/rpmesp.2020.373.6126

Keywords:

2019 Novel Coronavirus Disease, Kawasaki Disease, Child, Intravenous Immune globulins

Abstract

During the COVID-19 pandemic, a new, severe and unusual condition called Multisystem Inflammatory Syndrome in children emerged, from which there is still much to learn. We report 8 children admitted to Instituto Nacional de Salud del Niño, in Lima, Perú. Their mean age was 5,1 years. Their clinical presentation included fever, acute gastrointestinal symptoms, ocular and mucocutaneous involvement. Four patients met criteria for classic Kawasaki Disease. All the patients had positive serology for SARS-CoV-2, abnormal complete blood counts and coagulation tests, and elevated inflammatory markers. Five had elevated liver enzymes and three had kidney involvement. Four patients met criteria for Macrophage Activation Syndrome. All of them received intravenous immune globulin, corticosteroids and aspirin. No coronary aneurysms were identified. Only one developed miocarditis, shock and was admitted to the Pediatric Intensive Care Unit. Most patients recovered successfully. Every child with fever, gastrointestinal and dermatological symptoms, associated with prior exposure to SARS-CoV-2, should be investigated for multi-systemic compromise.

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Author Biographies

  • Liz E. De Coll-Vela, Instituto Nacional de Salud del Niño Breña, Lima, Perú. Universidad Nacional Mayor de San Marcos, Lima, Perú. Médico Pediatra

    Médico Pediatra Asistente del Instituto Nacional de Salud del Niño. Docente de la Cátedra de Pediatría de la Universidad Nacional Mayor de San Marcos

  • Mariela K. Zamudio-Aquise, Instituto Nacional de Salud del Niño Breña, Lima, Perú. Universidad Peruana Cayetano Heredia, Lima, Perú. Médico Pediatra Neumólogo

    Médico Pediatra Neumólogo

  • Héctor Nuñez-Paucar, Instituto Nacional de Salud del Niño Breña, Lima, Perú. Universidad Nacional Mayor de San Marcos, Lima, Perú. Médico Pediatra Neumólogo
    Médico Pediatra Neumólogo
  • Raúl R. Bernal-Mancilla, Instituto Nacional de Salud del Niño Breña, Lima, Perú. Universidad Nacional Mayor de San Marcos, Lima, Perú. Médico Pediatra
    Médico Pediatra
  • Sandra C. Schult-Montoya, Instituto Nacional de Salud del Niño Breña, Lima, Perú. Universidad Nacional Mayor de San Marcos, Lima, Perú. Médico Pediatra
    Médico Pediatra
  • Manuel Ccorahua-De La Paz, Instituto Nacional de Salud del Niño Breña, Lima, Perú. Médico Pediatra Neumólogo
    Médico Pediatra Neumólogo
  • Cynthia L. Huby-Muñoz, Instituto Nacional de Salud del Niño Breña, Lima, Perú. Universidad de San Martín de Porres, Lima, Perú. Médico Pediatra
    Médico Pediatra
  • Carlos F. Castillo-Torres, Instituto Nacional de Salud del Niño Breña, Lima, Perú. Universidad de San Martín de Porres, Lima, Perú. Médico Pediatra
    Médico Pediatra
  • Jorge L. Candela-Herrera, Instituto Nacional de Salud del Niño Breña, Lima, Perú. Universidad Peruana Cayetano Heredia, Lima, Perú. Médico Pediatra Infectólogo
    Médico Pediatra Infectólogo
  • Franklin Aranda-Paniora, Instituto Nacional de Salud del Niño Breña, Lima, Perú. Universidad Nacional Mayor de San Marcos, Lima, Perú. Médico Pediatra
    Médico Pediatra
  • Raúl A. Rojas-Galarza, Instituto Nacional de Salud del Niño Breña, Lima, Perú. Médico Pediatra Gastroenterólogo.

    Médico Pediatra Gastroenterólogo.

Published

2020-08-31

Issue

Section

Case Report

How to Cite

1.
De Coll-Vela LE, Zamudio-Aquise MK, Nuñez-Paucar H, Bernal-Mancilla RR, Schult-Montoya SC, Ccorahua-De La Paz M, et al. COVID-19–associated multisystem inflammatory syndrome in children: case series at a pediatric hospital in Peru. Rev Peru Med Exp Salud Publica [Internet]. 2020 Aug. 31 [cited 2024 Jun. 23];37(3):559-65. Available from: https://rpmesp.ins.gob.pe/index.php/rpmesp/article/view/6126

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