Nanoparticles as drug transporters: a promising tool against tuberculosis

Authors

  • Julieta Luna-Herrera Departamento de Inmunología, Escuela Nacional de Ciencias Biológicas, Instituto Politécnico Nacional, Ciudad de México, México. Química bacterióloga parasitóloga, doctora en Inmunología https://orcid.org/0000-0001-8840-3602
  • Damián Eduardo Pérez-Martínez Instituto de Ciencias de la Salud, Universidad Veracruzana, Xalapa, Veracruz, México. biólogo; maestro en Salud Pública https://orcid.org/0000-0002-8217-0761
  • Virginia Margarita Barradas-Hernández Instituto de Salud Pública, Universidad Veracruzana, Xalapa, Veracruz, México. médico cirujano https://orcid.org/0000-0001-8175-0521
  • Roberto Zenteno-Cuevas Instituto de Salud Pública, Universidad Veracruzana, Xalapa, Veracruz, México. biólogo doctor en Ciencias https://orcid.org/0000-0001-9597-127X

DOI:

https://doi.org/10.17843/rpmesp.2021.381.6156

Keywords:

Tuberculosis, Nanoparticles, Antimicrobial Drug Resistance, Anti-Infective Agents, Biological Transport

Abstract

The World Health Organization (WHO) places Tuberculosis (TB) as one of the most important health problems today. According to the WHO, this disease requires novel actions to control its expansion and, in this way, achieve one of the goals established in the sustainable development goals: to reduce TB morbidity and incidence by 2030 and regain control. To achieve this goal, the tools currently used for diagnosis and treatment are no longer adequate. In this sense, it is necessary to develop new drugs and vaccines, as well as novel drug administration procedures that generate a better response, reduce times, and optimize treatments. Nanotechnology has incorporated in recent years a considerable number of new tools that significantly increase the diversity of mechanisms for the administration of anti-tuberculosis drugs. Therefore, the present review briefly describes the current state of drug resistance in tuberculosis, as well as the general characteristics of nanoparticles being evaluated as tools to transport new antibiotics against tuberculosis.

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Published

2021-02-01

Issue

Section

Review

How to Cite

1.
Luna-Herrera J, Pérez-Martínez DE, Barradas-Hernández VM, Zenteno-Cuevas R. Nanoparticles as drug transporters: a promising tool against tuberculosis. Rev Peru Med Exp Salud Publica [Internet]. 2021 Feb. 1 [cited 2024 Jun. 15];38(1):143-52. Available from: https://rpmesp.ins.gob.pe/index.php/rpmesp/article/view/6156

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