Early puberty and thoracic mass: presentation of a case

Authors

  • María Nataly Laredo Reyna Instituto Nacional de Salud del Niño. Lima, Perú. Médico pediatra
  • Juan Manuel Falen Bogio Facultad de Medicina, Universidad Nacional Federico Villareal. Lima, Perú. médico endocrinólogo
  • Roxana Lipa Chancolla Instituto Nacional de Salud del Niño. Lima, Perú. médico patólogo clínico
  • Oswaldo Núñez Almache Instituto Nacional de Salud del Niño. Lima, Perú. médico endocrinologo pediatra
  • Paola Pinto Instituto Nacional de Salud del Niño. Lima, Perú. Médico pediatra
  • Oscar Espinoza Robles Instituto Nacional de Salud del Niño. Lima, Perú. Médico pediatra
  • Eliana Chávez Instituto Nacional de Salud del Niño. Lima, Perú. Médico pediatra
  • María Isabel Rojas Gabulli Instituto Nacional de Salud del Niño. Lima, Perú. Facultad de Medicina, Universidad Nacional Federico Villareal. Lima, Perú. médico endocrinólogo
  • Carlos Del Aguila Villar Instituto Nacional de Salud del Niño. Lima, Perú. Facultad de Medicina, Universidad Nacional Federico Villareal. Lima, Perú. Médico pediatra

DOI:

https://doi.org/10.17843/rpmesp.2014.313.99

Keywords:

Puberty, precocious, Dyspnea, Thorax, Teratoma

Abstract

A case is reported of a 7 year old patient with progressive dyspnea and genital development according to Marshall and Tanner criteria at the G2 VP3 stage. A mass of regular and well-defined borders was found in the chest, with calcifications and cystic areas of heterogeneous content. Basal measurements of FSH, LH and testosterone were <10 mIU/mL, 12.2 mIU/mL and 724 ng/dL, respectively. α-fetoprotein was 145.1 ng/mL. Excising the tumor improved respiratory symptoms, diminished hormone levels and stopped the process of precocious puberty. Pathology of the mediastinal tumor corresponded to a germ cell tumor with a predominant component of mature teratoma and choriocarcinoma. Neoplastic causes of precocious puberty are uncommon; its diagnosis is essential in order to provide timely treatment.

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Published

2014-09-25

Issue

Section

Case Report

How to Cite

1.
Laredo Reyna MN, Falen Bogio JM, Lipa Chancolla R, Núñez Almache O, Pinto P, Espinoza Robles O, et al. Early puberty and thoracic mass: presentation of a case. Rev Peru Med Exp Salud Publica [Internet]. 2014 Sep. 25 [cited 2024 Dec. 1];31(3). Available from: https://rpmesp.ins.gob.pe/index.php/rpmesp/article/view/99