Genotipificación del virus de la hepatitis B de pacientes de áreas endémicas del Perú

Gisely Hijar; Magna Suárez; Carlos Padilla; César Cabezas

doi:10.17843/rpmesp.2007.244.1137

Authors

Gisely Hijar Centro Nacional de Salud Pública, Instituto Nacional de Salud. Lima, Perú. Biólogo molecular.
Magna Suárez Centro Nacional de Salud Pública, Instituto Nacional de Salud. Lima, Perú. Bióloga
Carlos Padilla Centro Nacional de Salud Pública, Instituto Nacional de Salud. Lima, Perú. Biólogo molecular.
César Cabezas Centro Nacional de Salud Pública, Instituto Nacional de Salud. Lima, Perú. Instituto de Medicina Tropical “Daniel A. Carrión”, Universidad Nacional Mayor de San Marcos. Lima, Perú. Médico infectólogo.

DOI:

https://doi.org/10.17843/rpmesp.2007.244.1137

Keywords:

Hepatitis B/ virology, Genotype, Perú

Abstract

In the world there are more than 350 million of chronic carriers with hepatitis B virus (HBV), in Peru the prevalence of this virus is varied. There are hyperendemic areas in the Amazon Region and some valleys of the Eastern slope of the Andean such as Abancay and Huanta. The objective of this study was to determine preliminary the genotypes of the HBV present in serologic samples from Ancash, Ayacucho, Lima, Loreto and Ucayali areas. The analysis of partial S region HBV sequence was realized from twelve antigen e (HBeAg) positive serums. The result of this analysis indicates the presence of genotype F (subtype adw4) in all the analyzed samples.