Estado de hierro y propuesta de ajuste de hemoglobina por altitud en niños de 6 a 8 meses residentes en Lima, Arequipa, Cusco y Puno

Juan Pablo Aparco; Gabriela Santos-Antonio; William Bautista-Olortegui; Katherine Alvis-Chirinos; Patricia Velarde-Delgado; Paul Hinojosa-Mamani; Gilmer Solis-Sanchez; Flor Eliana Santa Cruz; Nelly Zavaleta

doi:10.17843/rpmesp.2023.404.12573

Authors

Juan Pablo Aparco Centro Nacional de Alimentación, Nutrición y Vida Saludable, Instituto Nacional de Salud, (INS), Lima, Perú. https://orcid.org/0000-0001-9159-7997
Gabriela Santos-Antonio Centro Nacional de Alimentación, Nutrición y Vida Saludable, Instituto Nacional de Salud, (INS), Lima, Perú. https://orcid.org/0000-0002-7690-0676
William Bautista-Olortegui Centro Nacional de Alimentación, Nutrición y Vida Saludable, Instituto Nacional de Salud, (INS), Lima, Perú https://orcid.org/0000-0002-1815-8952
Katherine Alvis-Chirinos Centro Nacional de Alimentación, Nutrición y Vida Saludable, Instituto Nacional de Salud, (INS), Lima, Perú. https://orcid.org/0000-0003-3863-3770
Patricia Velarde-Delgado Centro Nacional de Alimentación y Nutrición, Instituto Nacional de Salud. (INS), Lima, Perú https://orcid.org/0000-0002-6981-6150
Paul Hinojosa-Mamani Centro Nacional de Alimentación, Nutrición y Vida Saludable, Instituto Nacional de Salud, (INS), Lima, Perú. https://orcid.org/0000-0002-1592-4586
Gilmer Solis-Sanchez Centro Nacional de Alimentación, Nutrición y Vida Saludable, Instituto Nacional de Salud, (INS), Lima, Perú https://orcid.org/0000-0001-7084-088X
Flor Eliana Santa Cruz Dirección General de Intervenciones Estratégicas en Salud Pública, Ministerio de Salud (MINSA), Lima, Perú. https://orcid.org/0000-0003-3352-2123
Nelly Zavaleta Instituto de Investigación Nutricional (IIN), Lima, Perú https://orcid.org/0000-0002-6929-5834

DOI:

https://doi.org/10.17843/rpmesp.2023.404.12573

Keywords:

Child, Anemia, Altitude, Iron-Deficiency, Peru

Abstract

Objective. To describe the iron status profile and to propose hemoglobin adjustment factors for altitude for children aged 6 to 8 months in Lima, Arequipa, Cusco and Puno. Materials and methods. Cross-sectional study in children aged 6 to 8 months from four cities. We measured hemoglobin and other iron biomarkers, C-reactive protein (CRP), among others. To estimate the adjustment equation, we applied an exponential regression. We excluded children with iron deficiency (ID) and/or inflammation. Results. The proportions of ID were higher in Puno and Arequipa, while inflammation did not exceed 19% in any of the cities. Hemoglobin showed an exponential increase at higher altitude. The adjustment equation was: 10.34249 x (1.00007 ^ Alt). Conclusions. Children residing in Arequipa and Puno showed higher rates of ID and lower iron reserves; furthermore, the increase in hemoglobin by altitude was exponential, showing the need to adjust hemoglobin at altitude.

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