Effect of alcohol consumption in the evolution of bipolar patients

Authors

  • Eloy Medina Departamento de Psiquiatría, Hospital Nacional Edgardo Rebagliati Martins. Lima, Perú. Facultad de Medicina, Universidad San Martín de Porras. Lima, Perú. Médico psiquiatra, Doctor en Medicina.
  • Helfer Molina Dirección de Salud V Lima Ciudad, Ministerio de Salud. Lima, Perú. Estadístico.
  • Sixto E. Sánchez Facultad de Medicina, Universidad San Martín de Porras. Lima, Perú. Oficina General de Investigación y Transferencia Tecnológica, Instituto Nacional de Salud. Lima, Perú. Médico epidemiólogo.

DOI:

https://doi.org/10.17843/rpmesp.2008.253.1277

Keywords:

Bipolar disorder, Alcohol consumption, Cocaine, Cohort studies

Abstract

Objective. To evaluate the effect of alcohol consumption in the evolution of bipolar patients. Material and methods. 170 record files of outpatients with bipolar disorder, seen at Victor Larco Herrera Hospital during 2001-2005 were included. Data were registered in a data collection form and then in a database in SPSS 15. OR and CI 95% were calculated in order to assess the association between alcohol consumption and the good or bad evolution of the bipolar patient. Logistic regression was used to control potential confounders. Results. Mean age of participants was 45 years, 29.4% were male and 31.8% were alcohol consumers. 8.5% of participants had bipolar I disease and 14.1% had bipolar II disease. Median number of recurrences and suicide intents in alcohol consumers was 4 and one respectively, in comparison with 1 and 0 in those not consumers. From 40 patients with bad evolution, 77.5% were alcohol consumers (with or without cocaine), in comparison with only 17.7% of the 130 patients who had good evolution (OR: 9.5; CI 95%: 2.6 - 34.9). Patients who consumed both, alcohol and cocaine had higher risk of having a bad evolution (OR: 26.8; CI 95%: 6.9 - 104.2). Conclusions. Comparing with not consumers, alcohol abuse affected evolution and prognosis of bipolar patients. This is why bipolar patients who are alcohol consumers should be followed up more accurately in order to avoid recurrences and other bad outcomes.

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Published

2008-09-30

Issue

Section

Research Articles

How to Cite

1.
Medina E, Molina H, Sánchez SE. Effect of alcohol consumption in the evolution of bipolar patients. Rev Peru Med Exp Salud Publica [Internet]. 2008 Sep. 30 [cited 2024 Mar. 28];25(3). Available from: https://rpmesp.ins.gob.pe/index.php/rpmesp/article/view/1277

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