Use of SARS-CoV-2 genomes to estimate the effective reproductive number (Rt) in Peru during March – April 2020

Authors

  • Pedro E. Romero Departamento de Ciencias Biológicas y Fisiológicas. Facultad de Ciencias y Filosofía, Universidad Peruana Cayetano Heredia, Lima, Perú. Biólogo con mención en Genética y Biología Celular, doctor en Ciencias Naturales http://orcid.org/0000-0001-9947-3868
  • Milagros Sánchez-Yupari Facultad de Ciencias y Filosofía, Universidad Peruana Cayetano Heredia, Lima, Perú. bachiller en Ciencias https://orcid.org/0000-0003-2113-0253
  • Stephanie Montero Unidad de Investigación en Enfermedades Emergentes y Cambio Climático, Facultad de Salud Pública y Administración, Universidad Peruana Cayetano Heredia, Lima, Perú. bióloga microbióloga parasitóloga https://orcid.org/0000-0002-8147-8318
  • Pablo Tsukayama Departamento de Ciencias Celulares y Moleculares, Facultad de Ciencias y Filosofía, Universidad Peruana Cayetano Heredia, Lima, Perú. licenciado en Biología, doctor en Filosofía en Biología y Ciencias Biomédicas https://orcid.org/0000-0002-1669-2553

DOI:

https://doi.org/10.17843/rpmesp.2021.382.6417

Keywords:

Análisis Bayesiano, Bases de Datos de Ácidos Nucleicos, COVID-19, Epidemiología Molecular, Filogenómica, Genómica, Modelos Epidemiológicos, Perú, SARS-CoV-2, Vigilancia

Abstract

The understanding of COVID-19, caused by the SARS-CoV-2, is essential to improve evidence-based public health policies. The effective reproductive number (Rt) in Peru was estimated using information from 113 complete genomes sequenced by the Instituto Nacional de Salud del Perú (INS), available in the GISAID public database. The Rt trend during March and April of 2020 was found to be similar to results from other epidemiological reports. The Rt decreased during the first two weeks of March. Its lowest value was reported during the week after the quarantine began. The Rt increased moderately after the second week of April. The implication of early decisions taken to mitigate the transmission are discussed. Genomic surveillance will be necessary to understand the transmission and evolution of SARS-CoV-2 in Peru, and will complement the epidemiological information.

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Published

2021-03-30

Issue

Section

Brief Report

How to Cite

1.
Romero PE, Sánchez-Yupari M, Montero S, Tsukayama P. Use of SARS-CoV-2 genomes to estimate the effective reproductive number (Rt) in Peru during March – April 2020. Rev Peru Med Exp Salud Publica [Internet]. 2021 Mar. 30 [cited 2024 May 23];38(2):267-71. Available from: https://rpmesp.ins.gob.pe/index.php/rpmesp/article/view/6417

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