Identification of multidrug-resistant enterobacteriaceae in fecal samples from infants residing in Talara, Piura, Peru

Authors

DOI:

https://doi.org/10.17843/rpmesp.2022.394.11870

Keywords:

Newborn, Escherichia coli, Drug Resistance, beta-Lactamases, Quinolones, Peru, Coliforms

Abstract

Fecal colonization in infants by antimicrobial-resistant bacteria is a potential risk for future antibiotic therapy. We determine the frequency and sociodemographic characteristics of infants who are fecal carriers of Enterobacteriaceae resistant to ciprofloxacin (PFRC) and their associated resistance genes. We obtainfecal samples from 41 nursing children residing in the district of Talara - Piura, Peru, were analyzed in 2019. The presence of 3 quinolone resistance genes was evaluated: aac(6’)-Ib-cr, qnrB and oqxA and 2 of beta-lactamases: blaCTX-M,blaPER-2. 68% of infants were PFRC, Escherichia coli (83.3%) was the most frequent. Genotypic analysis detected: oqxA (41.1%), qnrB (26.7%) and aac(6’)-Ib-cr (20%) and the blaCTX-M gene in 93.3% of the isolates with beta-lactamases. The high frequency of PFRC alert us to the potential risk in the loss of usefulness of this antibiotic family in the study area.

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References

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Published

2022-12-09

Issue

Section

Brief Report

How to Cite

1.
Gonzales-Rodríguez AO, Castillo Horna JI, Gonzales Escalante E. Identification of multidrug-resistant enterobacteriaceae in fecal samples from infants residing in Talara, Piura, Peru. Rev Peru Med Exp Salud Publica [Internet]. 2022 Dec. 9 [cited 2024 May 21];39(4):456-62. Available from: https://rpmesp.ins.gob.pe/index.php/rpmesp/article/view/11870