Clinical and molecular characteristics of influenza outbreak in two military bases in Tumbes, Perú 2007

Authors

  • Tatiana Saldarriaga US Naval Medical Research Center Detachment (NMRCD). Lima, Perú. Médico.
  • V. Alberto Laguna-Torres US Naval Medical Research Center Detachment (NMRCD). Lima, Perú. Médico. Doctor en Ciencias.
  • Juan Arrasco Oficina de Epidemiología, Dirección Regional de Salud Tumbes. Tumbes, Perú. Médico.
  • Luis Guillén 1era Brigada de Infantería Ejército del Perú. Tumbes, Perú. Enfermero Militar.
  • Juan Águila 1era Brigada de Infantería Ejército del Perú. Tumbes, Perú. Enfermero Militar.
  • Patricia Aguilar US Naval Medical Research Center Detachment (NMRCD). Lima, Perú. Doctor en Ciencias.
  • Merly Sovero US Naval Medical Research Center Detachment (NMRCD). Lima, Perú. Bióloga.
  • Juan Pérez US Naval Medical Research Center Detachment (NMRCD). Lima, Perú. Ingeniero analista / programador.
  • Jane Ríos US Naval Medical Research Center Detachment (NMRCD). Lima, Perú. Bióloga.
  • María Gamero US Naval Medical Research Center Detachment (NMRCD). Lima, Perú. Bióloga.
  • Rommell González Centro de Salud Zarumilla, Ministerio de Salud. Tumbes, Perú. Médico.
  • Tadeusz Kochel US Naval Medical Research Center Detachment (NMRCD). Lima, Perú. Doctor en Ciencias.

DOI:

https://doi.org/10.17843/rpmesp.2008.251.1234

Keywords:

Human Influenza, Outbreak, Militar personnel, Perú

Abstract

Objective. To describe an Influenza outbreak in two military bases in Tumbes, department located in northern Peru. Material and methods. In patients within 5 days of symptoms the Ministry of Health case definition of Influenza-like illness was used. Nasal swabs were taken for Rapid Influenza Test (RIT) and throat swab for viral isolation, three cell lines (MDCK, VERO, LLCMK2) were used. For Influenza B genotypification we made a partial sequencing of hemaglutinine region of 898 pair bases, having 2007 vaccine strain B/Florida/4/2006 as a model. For Influenza A genotypification we analysed 958 pair bases, having 2007 vaccine strain A/Brisbane/10/2007 (H3N2) as a model. Results. We took 124 samples, 20 from military base (MB) # 1 and 104 from MB # 2. RIT promptly identified 41 positive cases: Flu B: 27, Flu A: 02, Flu: 12, with 62% of sensibility and specificity 100%. Finally, 66 cases were confirmed by virus isolation, 54 Flu B and 12 Flu A. Genotypification showed that isolates were genetically similar to Influenza B/Texas/4/2006 (n=34) and A/Texas/91/2007 (H3N2) (n=7). Most common symptoms found were fever, headache, malaise, cough, sore throat, myalgias and rinorrheae. Control strategies consisted to identify probable cases and to isolate them in a special room and to wear facemasks. Conclusions. We confirmed 66 cases by cellular culture. Isolates were genetically similar to Influenza B/Texas/4/2006 and A/Texas/91/2007 (H3N2).

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Published

2008-03-31

Issue

Section

Research Articles

How to Cite

1.
Saldarriaga T, Laguna-Torres VA, Arrasco J, Guillén L, Águila J, Aguilar P, et al. Clinical and molecular characteristics of influenza outbreak in two military bases in Tumbes, Perú 2007. Rev Peru Med Exp Salud Publica [Internet]. 2008 Mar. 31 [cited 2024 Jun. 12];25(1). Available from: https://rpmesp.ins.gob.pe/index.php/rpmesp/article/view/1234

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