Infección por SARS-CoV-2 en el embarazo: características clínicas y trasmisión vertical en un hospital de referencia de Perú

Claudia Aracelli Urbina-Alvarez; Julio Cesar Sifuentes-Alvarez; Juan Felipe Moreno-Bocanegra; Kevin Vasquez-Sandoval; Lilia Huiza- Espinoza; Mauricio La Rosa-De los Rios; Juan Carlos Gomez De La Torre-Pretell; Claudia Fiorella Barletta-Carillo

doi:10.17843/rpmesp.2024.412.13293

Authors

Claudia Aracelli Urbina-Alvarez Hospital Nacional Edgardo Rebagliati Martins, Lima, Perú https://orcid.org/0000-0002-6928-4377
Julio Cesar Sifuentes-Alvarez Hospital Nacional Edgardo Rebagliati Martins, Lima, Perú https://orcid.org/0000-0002-4411-7353
Juan Felipe Moreno-Bocanegra Hospital Nacional Edgardo Rebagliati Martins, Lima, Perú https://orcid.org/0000-0001-6284-8670
Kevin Vasquez-Sandoval Hospital Nacional Edgardo Rebagliati Martins, Lima, Perú https://orcid.org/0000-0003-4390-7748
Lilia Huiza- Espinoza Hospital San Bartolomé, Lima, Perú https://orcid.org/0000-0002-3120-7413
Mauricio La Rosa-De los Rios Universidad De Texas Medical Branch, Texas, Estados Unidos. Universidad Peruana Cayetano Heredia, Lima, Perú https://orcid.org/0000-0003-0183-1706
Juan Carlos Gomez De La Torre-Pretell Laboratorio ROE, Lima, Perú https://orcid.org/0000-0003-4566-2027
Claudia Fiorella Barletta-Carillo Sequence Reference Lab, Lima, Perú. Universidad Nacional Mayor de San Marcos, Lima, Perú https://orcid.org/0000-0001-9982-5368

DOI:

https://doi.org/10.17843/rpmesp.2024.412.13293

Keywords:

Infectious disease transmission vertical, COVID-19, Pregnancy, Newborn

Abstract

The study carried out in the Department of Gynecology and Obstetrics of the Edgardo Rebagliati Martins National Hospital (HNERM) aimed to analyze the vertical transmission of the SARS-CoV-2 virus in pregnant women with COVID-19. Twelve pregnant women who met the established inclusion criteria were included. Real-time PCR (RT-PCR) diagnostic testing for SARS-CoV-2 was performed during the admission of each pregnant patient, and placenta samples were collected for pathological evaluation. The results showed that vertical transmission of the virus was rare, with an overall low positivity rate in newborns. Although the study has limitations, such as the small number of cases and the lack of electron microscope analysis, it constitutes the first attempt in Peru to evaluate vertical transmission. It is concluded that more research is needed to better understand the relationship between COVID-19 infection and complications during pregnancy.

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