Síndrome de Guillain-Barre asociado a dengue previo: reporte de caso

Manuel Sanchez-Landers; Arnold Frank Rodriguez-Benites

doi:10.17843/rpmesp.2025.421.13893

Authors

Manuel Sanchez-Landers Facultad de Medicina, Universidad Nacional de Trujillo, Trujillo, Perú. Departamento de Emergencia y Cuidados Críticos del Hospital Belén de Trujillo. Trujillo, Perú. https://orcid.org/0000-0001-9777-670X
Arnold Frank Rodriguez-Benites Facultad de Medicina, Universidad Nacional de Trujillo, Trujillo, Perú. https://orcid.org/0000-0003-4221-398X

DOI:

https://doi.org/10.17843/rpmesp.2025.421.13893

Keywords:

Polyneuropathy, Arbovirus Infection, Arthropod Vectors, Intravenous Immunoglobulins, Peru

Abstract

Guillain-Barré syndrome is a potentially severe autoimmune inflammatory polyneuropathy, which is usually associated with previous infections. Dengue is the most common arbovirus infection worldwide, being endemic in tropical and subtropical areas such as Peru. Scientific literature shows some reports of dengue with neurological complications, but its pathophysiology is not well understood. We present the case of a woman from an area endemic for dengue with Guillain-Barré syndrome with a disability scale of 4/6 on the Hughes scale, confirmed by albumin-cytological dissociation, and previous infection with dengue virus confirmed with a positive serum ELISA IgM test. The patient’s progress was favorable after receiving intravenous immunoglobulin. It is important to consider this viral infection as a probable risk factor for developing Guillain-Barré syndrome.

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