Effect of intravenous infusion of Kcl on the electrocardiogram and serum potassium in dogs with normal renal function

Authors

  • Jessica Bravo-Zúñiga Servicio de Nefrologia, Departamento de Medicina. Universidad Peruana Cayetano Heredia, Lima, Peru.
  • Julio Huapaya Universidad Peruana Cayetano Heredia, Lima, Peru.
  • Cesar Valencia Universidad Peruana Cayetano Heredia, Lima, Peru.
  • Sandra Bezada Universidad Peruana Cayetano Heredia, Lima, Peru.
  • Cristian Leon Servicio de Nefrologia, Departamento de Medicina. Universidad Peruana Cayetano Heredia, Lima, Peru.
  • Renato Ferrandiz-Espadin Universidad Peruana Cayetano Heredia, Lima, Peru.
  • Javier Cieza Servicio de Nefrologia, Departamento de Medicina. Universidad Peruana Cayetano Heredia, Lima, Peru.

DOI:

https://doi.org/10.17843/rpmesp.2015.321.1583

Keywords:

Potassium, Electrocardiography, endovenous infusions

Abstract

Variations in serum potassium (K+) and electrocardiographic changes at different infusion speeds of intravenous K+ were studied in dogs. Solutions of 20, 40, 60 and 80 mEq of K+ were infused in one hour to dogs with normal renal function and normal serum K+. Nine dogs were studied: three without prior hydration and six with previous hydration. Infusing 20 mEq / hour of K+ produced an increase in heart rate without changes in the electrocardiogram. With 40 mEq / hour there were changes in the “t” and “p” waves, and with 60 and 80 mEq / hour, alterations consistent with cardiac ischemia and ventricular tachycardia. Dogs without hydration had more obvious and fatal electrocardiographic changes. Doses of 20 mEq / hour of K + caused no morbidity or mortality in the animals studied. Higher doses showed various complications which depended on the hydration status of the animal, its urinary flow and potassium level.

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Published

2015-04-02

Issue

Section

Research Articles

How to Cite

1.
Bravo-Zúñiga J, Huapaya J, Valencia C, Bezada S, Leon C, Ferrandiz-Espadin R, et al. Effect of intravenous infusion of Kcl on the electrocardiogram and serum potassium in dogs with normal renal function. Rev Peru Med Exp Salud Publica [Internet]. 2015 Apr. 2 [cited 2024 Jun. 13];32(1):110-6. Available from: https://rpmesp.ins.gob.pe/index.php/rpmesp/article/view/1583

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