Performance of cognitive brief test in elderly patients with dementia in advanced stage living in an urban community of Lima, Peru

Authors

  • Nilton Custodio Servicio de Neurología, Instituto Peruano de Neurociencias. Lima, Perú. Servicio de Neurología, Clínica Internacional. Lima, Perú. Médico neurólogo; magíster en Neurociencias
  • Carlos Alva-Diaz Servicio de Neurología, Hospital Nacional Daniel Alcides Carrión. Callao, Perú. Red de Eficacia Clínica y Sanitaria REDECS. Lima, Perú. médico cirujano
  • Yahaira Becerra-Becerra Servicio de Geriatría, Hospital Militar Geriátrico. Lima, Perú. Red de Eficacia Clínica y Sanitaria REDECS. Lima, Perú. médico cirujano
  • Rosa Montesinos Unidad de Medicina de Rehabilitación, Instituto Peruano de Neurociencias. Lima, Perú. médico rehabilitador
  • David Lira Servicio de Neurología, Instituto Peruano de Neurociencias. Lima, Perú. Servicio de Neurología, Clínica Internacional. Lima, Perú. Médico neurólogo magíster en Salud Pública
  • Eder Herrera-Pérez Unidad de Proyectos de Investigación, Instituto de Salud del Niño. Lima, Perú. médico cirujano
  • Sheila Castro-Suárez Servicio de Neurología, Instituto Peruano de Neurociencias. Lima, Perú. Servicio de Neurología, Clínica Internacional. Lima, Perú. Servicio de Neurología de la Conducta, Instituto Nacional de Ciencias Neurológicas. Lima, Perú. Médico neurólogo
  • José Cuenca-Alfaro Unidad de Neuropsicología, Instituto Peruano de Neurociencias. Lima, Perú. psicólogo.
  • Elizabeth Valeriano-Lorenzo Unidad de Neuropsicología, Instituto Peruano de Neurociencias. Lima, Perú. psicólogo.

DOI:

https://doi.org/10.17843/rpmesp.2016.334.2549

Keywords:

Dementia, Differential diagnosis, Alzheimer´s disease, Sensitivity and Specificity, Diagnostic Techniques, Neurological

Abstract

Objectives. Evaluate the performance of clock drawing test- Manos versión (PDR-M) and Mini Mental State Examination - Peruvian version (MMSE) to detect dementia in a sample based on urban community of Lima, Peru. Materials and methods. This study is a secondary analysis database, observational, analytical and cross-sectional, the gold standard was the clinical and the neuropsychological evaluations together. Performance testing individually and in combination were evaluated.. Data were obtained from prevalence study conducted in 2008 in Cercado de Lima. Results. MMSE performance for evaluation of patients with dementia of any kind showed sensitivity of 64,1%, specificity of 84,1%, PPV of 24.4%, NPV of 96.7%, PLR of 4,03 and NLR of 0,43. PDR-M showed sensitivity of 89,3%, specificity of 98,1%, PPV of 79.3%, NPV of 99.1%, PLR of 47,79 and NLR of 0,11. When both tests were applied, and at least one of them was positive, they showed sensitivity 98.1%, specificity 84.1%, PPV of 33.1%, NPV of 99.8%, PLR of 6,17 and NLR of 0,02. When performing separate analysis of Alzheimer-type dementia and non- Alzheimer dementia, the values of the parameters do not differ substantially from those obtained for dementia of any kind. Conclussions. The combination of MMSE and PDR-M show good discriminative ability to detect moderate and severe dementia in population living in urban community in Lima.

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Published

2016-12-13

Issue

Section

Original Article

How to Cite

1.
Custodio N, Alva-Diaz C, Becerra-Becerra Y, Montesinos R, Lira D, Herrera-Pérez E, et al. Performance of cognitive brief test in elderly patients with dementia in advanced stage living in an urban community of Lima, Peru. Rev Peru Med Exp Salud Publica [Internet]. 2016 Dec. 13 [cited 2024 May 23];33(4):662-9. Available from: https://rpmesp.ins.gob.pe/index.php/rpmesp/article/view/2549