Ceftriaxone-resistant Streptococcus pneumoniae meningitis: case report

Authors

  • Marcos Saavedra-Velasco Servicio de Infectología, Hospital Nacional “Edgardo Rebagliati Martins”. Lima, Perú Universidad Ricardo Palma. Lima, Perú. Médico-Cirujano; Médico especialista en Infectología y enfermedades tropicales
  • Mariel Tapia-Cruz Servicio de Infectología, Hospital Nacional “Edgardo Rebagliati Martins”. Lima, Perú Médico-Cirujano
  • J. Antonio Grandez-Urbina Universidad Ricardo Palma. Lima, Perú. Universidad Continental. Lima, Perú. Médico-Cirujano
  • Saarah Zegarra Del Rosario-Alvarado Universidad Ricardo Palma. Lima, Perú. Médico-Cirujano
  • Fernando Mendo-Urbina Servicio de Infectología, Hospital Nacional “Edgardo Rebagliati Martins”. Lima, Perú Médico-Cirujano; Médico especialista en Infectología y enfermedades tropicales
  • Rafael Pichardo-Rodriguez Servicio de Infectología, Hospital Nacional “Edgardo Rebagliati Martins”. Lima, Perú Universidad Ricardo Palma. Lima, Perú. Médico-Cirujano

DOI:

https://doi.org/10.17843/rpmesp.2019.362.4036

Keywords:

Pneumococcal meningitis, Ceftriaxone, Microbial Drug Resistance

Abstract

Infectious meningitis is a medical emergency. Within the spectrum of infectious agents, the most important is Streptococcus pneumoniae, the most frequent etiological agent of bacterial meningitis. The initiation of empirical antimicrobial treatment bears great importance and considers third-generation cephalosporins as the first alternative. However, cases of ceftriaxone resistance have been reported in several regions of the world. This has become an emerging problem in need of reconsideration of the current empirical antibiotic treatment schemes. We present the case of a 56-year old man with acute infectious meningitis caused by ceftriaxone-resistant Streptococcus pneumoniae, who responded favorably to combined empirical treatment with ceftriaxone and vancomycin and to whom, during his hospital stay, the presence of hypothyroidism and mega cisterna magna was diagnosed.

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Published

2019-06-28

Issue

Section

Case Report

How to Cite

1.
Saavedra-Velasco M, Tapia-Cruz M, Grandez-Urbina JA, Zegarra Del Rosario-Alvarado S, Mendo-Urbina F, Pichardo-Rodriguez R. Ceftriaxone-resistant Streptococcus pneumoniae meningitis: case report. Rev Peru Med Exp Salud Publica [Internet]. 2019 Jun. 28 [cited 2024 Apr. 21];36(2):349-52. Available from: https://rpmesp.ins.gob.pe/index.php/rpmesp/article/view/4036

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