Linfoma de células T/NK extranasal primario en íleón

Rita López-Cabanillas; Cristian Espinoza-Escudero; Ademir Janampa-Apaza; Rolig Aliaga-Chávez

doi:10.17843/rpmesp.2020.371.4331

Authors

Rita López-Cabanillas Escuela de Medicina Humana, Universidad Nacional Mayor de San Marcos, Lima, Perú. Asociación para el Desarrollo de la Investigación Estudiantil en Ciencias de la Salud (ADIECS), Universidad Nacional Mayor de San Marcos, Lima, Perú. Estudiante de Medicina http://orcid.org/0000-0002-1091-8806
Cristian Espinoza-Escudero Escuela de Medicina Humana, Universidad Nacional Mayor de San Marcos, Lima, Perú. Sociedad Científica de San Fernando, Universidad Nacional Mayor de San Marcos, Lima, Perú. Estudiante de Medicina http://orcid.org/0000-0001-6049-1436
Ademir Janampa-Apaza Escuela de Medicina Humana, Universidad Nacional Mayor de San Marcos, Lima, Perú. Estudiante de Medicina
Rolig Aliaga-Chávez Servicio de Oncohematología Clínica, Hospital Nacional Arzobispo Loayza, Lima, Perú. médico oncólogo

DOI:

https://doi.org/10.17843/rpmesp.2020.371.4331

Keywords:

Extranodal NK-T-Cell Lymphoma, Epstein-Barr virus infections, Gastrointestinal tuberculosis, Crohn disease, Immunohistochemistry

Abstract

Primary extranodal Natural Killer / T cell lymphoma (NKTL) on gastrointestinal tract is an uncommon and aggressive neoplasm. We present the case of a 51-year-old immunocompetent patient with a 2-month history of abdominal pain. Colonoscopy findings showed ileal ulcerations, so studies were carried out to rule out Crohn’s disease and intestinal tuberculosis. Later, he developed intestinal obstruction. Exploratory laparotomy found a nodal conglomerate in the mesentery. Anatomical pathology confirmed the diagnosis of primary NKTL on the ileum. Chemotherapy was initiated but the patient asked for voluntary discharge because of his precarious condition. Two months after discharge the patient died. This lymphoma has been reported mainly in Asia and is possibly the first case in Peru. It has a dismal prognosis with overall survival of 8 months. Therefore, it is necessary to get an early diagnosis and begin therapy in a timely manner.