Cervical cancer incidence and patient survival in Manizales, Colombia, 2008-2012

Authors

  • Cristian C. Benitez-Restrepo Universidad de Caldas, Manizales, Colombia. Médico, especialista en Ginecología y Obstetricia http://orcid.org/0000-0002-9854-828X
  • Nelson E. Arias-Ortiz Grupo de Investigación en Promoción de la Salud y Prevención de la Enfermedad, Instituto de Investigaciones en Salud, Universidad de Caldas, Manizales, Colombia. Médico, especialista en Ginecología y Obstetricia; doctor en Salud Pública http://orcid.org/0000-0001-5093-3384
  • Walter A. Arboleda-Ruiz Grupo de investigación Materno-Perinatal. Universidad de Caldas, Manizales, Colombia. Médico, especialista en Ginecología y Obstetricia; mastólogo, doctor en Diseño y Creación. https://orcid.org/0000-0003-0665-3304

DOI:

https://doi.org/10.17843/rpmesp.2020.373.4838

Keywords:

Uterine Cervical Neoplasms, Incidence, Survival, Colombia

Abstract

Objective: To estimate the cervical cancer incidence and survival rates by histological subtype and stage in Manizales, Colombia during 2008-2012; and to compare the survival rate to the one from the previous five years. Materials and methods: Using population-based data, incidence rates by age were standardized for each histological subtype. Active and passive follow-up was performed to determine vital status and cause of death at 60 months. The Kaplan-Meier method and Cox models were adjusted to estimate overall survival by each covariant. Results: A total of 217 new cases were observed; with a mean incidence of 17.8 per 100,000 woman-years. Stages III-IV were more frequently observed in patients of medium and low socioeconomic status. At 5 years, the survival rate was 68.9%; ages over 70 years were associated with lower survival rates (p<0.001). Risk of death was 90% higher in patients with undifferentiated or unknown histological samples, when compared with those with squamous cell carcinoma (HR 1.9, 95% CI: 1.1-3.3). Likewise, the risk of death was 1.7 times higher for patients aged over 70 years (HR 2.7, 95% CI 1.6-4.8); and it was also found to be 3 times higher for stage III (HR 4.3, 95% CI: 1.8-10.2) and 7 times higher for stage IV (HR 8.7, 95% CI: 3.6-20.1), when compared with stage I. Conclusion: The incidence rate of cervical cancer in Manizales was found to be similar to the global and continental rates and lower than those from other Colombian cities with similar characteristics. Advanced stages were more frequent in women of low socioeconomic status. Survival was associated with age, histological subtype and staging.

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Author Biographies

  • Cristian C. Benitez-Restrepo, Universidad de Caldas, Manizales, Colombia. Médico, especialista en Ginecología y Obstetricia
    Especialista en Ginecología y Obstetricia
  • Nelson E. Arias-Ortiz, Grupo de Investigación en Promoción de la Salud y Prevención de la Enfermedad, Instituto de Investigaciones en Salud, Universidad de Caldas, Manizales, Colombia. Médico, especialista en Ginecología y Obstetricia; doctor en Salud Pública

    Profesor Asistente, Departamento de Salud Pública. Director Instituto de Investigaciones en Salud, Universidad de Caldas.

    Director Registro Poblacional de Cáncer de Manizales

     

  • Walter A. Arboleda-Ruiz, Grupo de investigación Materno-Perinatal. Universidad de Caldas, Manizales, Colombia. Médico, especialista en Ginecología y Obstetricia; mastólogo, doctor en Diseño y Creación.

    Profesor Asistente Departamento Materno-Infantil.

    Especialista en Ginecología y Obstetricia, Especialista en Mastología. SES-Hospital Universitario de Caldas

Published

2020-08-31

Issue

Section

Original Article

How to Cite

1.
Benitez-Restrepo CC, Arias-Ortiz NE, Arboleda-Ruiz WA. Cervical cancer incidence and patient survival in Manizales, Colombia, 2008-2012. Rev Peru Med Exp Salud Publica [Internet]. 2020 Aug. 31 [cited 2024 Oct. 13];37(3):438-45. Available from: https://rpmesp.ins.gob.pe/index.php/rpmesp/article/view/4838