Immunological and biochemical response from older adults with urinary tract infection to uropathogenic Escherichia coli virulence factors
Keywords:Nursing Homes, Elderly, Uropathogenic Escherichia coli, Biomarkers, Virulence Factors, Urinary Tract Infections, Immunology, Urine, Antioxidants, Cytokines
AbstractDescriptive study in which 24 urine samples from older adults with urinary tract infection (UTI), from nursing homes, were evaluated; in order to identify differences in the immune and biochemical response from older adults with UTI by Escherichia coli (E. coli) to major virulence factors in the pathogenesis of UTI. Iron concentration, TNF-α, IL-1β and antioxidant capacity in urine were determined. A relation was found between, an increase in iron and red blood cell concentration in urine, and the presence of the pap GII gene found in E. coli. It is concluded that older adults, with UTIs by E. coli with the gene pap GII, have increased tissue damage.
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Gonzales Rodriguez AO, Infante Varillas SF, Barrón Pastor HJ, Llimpe Mitma Y, Huerta Canales D, Wong Chero PA, Gutierrez C, Suarez Cunza S. Immunological and biochemical response from older adults with urinary tract infection to uropathogenic Escherichia coli virulence factors. Rev Peru Med Exp Salud Publica [nternet]. 2020 Jul. 14 [cited 2023 May 29];37(3):527-31. vailable from: https://rpmesp.ins.gob.pe/index.php/rpmesp/article/view/4918
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