Molecular characterization of carbapenemases in Peru during 2019

Authors

DOI:

https://doi.org/10.17843/rpmesp.2021.381.5882

Keywords:

Drug resistance, Carbapenemases, Acinetobacter, Enterobacteriaceae, Pseudomonas, Peru

Abstract

Resistance to carbapenems is a public health problem. This study presents the identification of carbapenemase enzymes in Enterobacteriaceae, Pseudomonas spp. and Acinetobacter spp. present in strains from 30 institutions that provide health services in Peru as part of the quality control process in diagnoses.
Phenotypic confirmation and enzymatic identification were performed using the Blue CARBA test and the synergy test with phenylboronic acid and ethylenediaminetetraacetic acid/sodium mercaptoacetic acid discs. 185 strains with carbapenemases were identified: 78 in Enterobacteriaceae, 61 in P. aeruginosa and 46 in Acinetobacter spp. The types of carbapenemases identified were: blaKPC, blaNDM, blaIMP, blaVIM, blaOXA-23, blaOXA-24, blaOXA-51 and the blaVIM/IMP co-production. It is important to strengthen the promotion of the rational use of antimicrobials and epidemiological surveillance in the country's hospitals.

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Published

2021-02-02

Issue

Section

Brief Report

How to Cite

1.
Mayta-Barrios MM, Ramirez-Illescas JJ, Pampa-Espinoza L, Yagui-Moscoso MJA. Molecular characterization of carbapenemases in Peru during 2019. Rev Peru Med Exp Salud Publica [Internet]. 2021 Feb. 2 [cited 2024 May 29];38(1):113-8. Available from: https://rpmesp.ins.gob.pe/index.php/rpmesp/article/view/5882

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