Molecular characterization of carbapenemases in Peru during 2019




Drug resistance, Carbapenemases, Acinetobacter, Enterobacteriaceae, Pseudomonas, Peru


Resistance to carbapenems is a public health problem. This study presents the identification of carbapenemase enzymes in Enterobacteriaceae, Pseudomonas spp. and Acinetobacter spp. present in strains from 30 institutions that provide health services in Peru as part of the quality control process in diagnoses.
Phenotypic confirmation and enzymatic identification were performed using the Blue CARBA test and the synergy test with phenylboronic acid and ethylenediaminetetraacetic acid/sodium mercaptoacetic acid discs. 185 strains with carbapenemases were identified: 78 in Enterobacteriaceae, 61 in P. aeruginosa and 46 in Acinetobacter spp. The types of carbapenemases identified were: blaKPC, blaNDM, blaIMP, blaVIM, blaOXA-23, blaOXA-24, blaOXA-51 and the blaVIM/IMP co-production. It is important to strengthen the promotion of the rational use of antimicrobials and epidemiological surveillance in the country's hospitals.


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Author Biography

Maritza Miriam Mayta-Barrios, Laboratorio de Referencia Nacional de Infecciones Intrahospitalarias, Instituto Nacional de Salud, Lima, Perú. Bióloga, maestra en Ciencias

Universidad Nacional de Trujillo. Magister en Ciencias, mencion Microbiologia Clinica.

Universidad Nacional San Agustin. Segunda Especialidad en Gestion Integral de Calidad de Laboratorios.

Universidad Nacional del Altiplano, Licenciada en Biologia, mencion en Microbiologia y Laboratorio clinico



How to Cite

Mayta-Barrios MM, Ramirez-Illescas JJ, Pampa-Espinoza L, Yagui-Moscoso MJA. Molecular characterization of carbapenemases in Peru during 2019. Rev Peru Med Exp Salud Publica [nternet]. 2021 Feb. 2 [cited 2023 Mar. 24];38(1):113-8. vailable from:



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