Clinical-epidemiological characteristics of dengue deaths during an outbreak in northern Peru

Authors

DOI:

https://doi.org/10.17843/rpmesp.2023.401.12148

Keywords:

Dengue fever, Mortality, Medical Records, Epidemiology, Peru

Abstract

Objective: To describe the clinical-epidemiological characteristics of patients who died from dengue during 2017. Methods: We conducted a retrospective study of the information related to cases of dengue deaths in the department of Piura. Results: We reviewed 24 medical records. Sixty-seven percent were women and 3 (12.5%) were pregnant. Diabetes (12.5%) and hypertension (16.7%) were the most frequent comorbidities. Previous dengue fever was reported in only 12.5%. The time from health care and death was 4.10 ± 5.34 days. Red blood cell transfusions were performed in 45.8%, plasma in 25%, platelets in 16.8% and cryoprecipitate in 16.8% of cases. Crystalloid therapy (91.7%) and treatment with vasoactive drugs (70.8%) were also frequent. In conclusion, mortality from severe dengue fever was predominantly in adult women, and the time of care from the first health facility to a specialized unit was prolonged.

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References

Santos LLM, de Aquino EC, Fernandes SM, Ternes YMF, Feres VC de R. Dengue, chikungunya, and Zika virus infections in Latin America

and the Caribbean: a systematic review. Rev Panam Salud Publica. 2023;47:e34. doi: 10.26633/RPSP.2023.34.

Rojas EM, Herrera VM, Miranda MC, Rojas DP, Gómez AM, Pallares C, et al. Clinical indicators of fatal dengue in two endemic areas of

Colombia: A hospital-based case-control study. Am J Trop Med Hyg. 2019;100(2):411–9. doi: 10.4269/ajtmh.17-0323.

Ramos-Castañeda J, Barreto Dos Santos F, Martínez-Vega R, Galvão de Araujo JM, Joint G, Sarti E. Dengue in Latin America: Systematic

review of molecular epidemiological trends. PLoS Negl Trop Dis. 2017;11(1):e0005224. doi: 10.1371/journal.pntd.0005224.

Centro Nacional de Epidemiología, Prevención y Control de Enfermedades [Internet]. CDC MINSA. [citado 27 de marzo de 2023].

Disponible en: https://www.dge.gob.pe/portalnuevo/.

Learning from El Niño Costero 2017: Opportunities for building resilience in PeruLearning from El Niño Costero 2017: Opportunities for building resilience in Peru [Internet]. iset. [citado 6 de marzo de 2023]. Disponible e n: https://www.i-s-e-t.org/publications-and-resources-1/learning-from-el-niño-costero-2017:-opportunities-for-building-resilience-in-peru.

Dengue guidelines, for diagnosis, treatment, prevention and control [Internet]. World Health Organization; 2009 [citado 27 de marzo

de 2023]. Disponible en: https://www.who.int/publications/i/item/9789241547871.

Ministerio de Salud [Internet]. [citado 27 de marzo de 2023]. Disponible en: https://www.gob.pe/institucion/minsa/normas-legales/

-071-2017.

Huy NT, Van Giang T, Thuy DHD, Kikuchi M, Hien TT, Zamora J, et al. Factors associated with dengue shock syndrome: a systematic

review and meta-analysis. PLoS Negl Trop Dis. 2013;7(9):e2412. doi: 10.1371/journal.pntd.0002412.

Anders KL, Nguyet NM, Chau NVV, Hung NT, Thuy TT, Lien LB, et al. Epidemiological factors associated with dengue shock syndrome

and mortality in hospitalized dengue patients in Ho Chi Minh City, Vietnam. Am J Trop Med Hyg [Internet]. enero de 2011;84(1):127–34. Disponible en: http://dx.doi.org/10.4269/ajtmh.2011.10-0476.

Romero-Santacruz E, Lira-Canul JJ, Pacheco-Tugores F, Palma-Chan AG. Dengue neonatal. Presentación de casos clínicos. Ginecol Obstet Mex. 2015;83(05):308–15.

Fonseca SNS. Changing epidemiology of dengue fever in children in South America. Curr Opin Pediatr [Internet]. 1 de abril de

;35(2):147–54. doi: 10.1097/MOP.0000000000001220.

World Health Organization. Global strategy for dengue prevention and control 2012-2020 [Internet]. Genève, Switzerland: World Health Organization; 2012 [citado 6 de marzo de 2023]. Disponible en: https://apps.who.int/iris/handle/10665/75303.

Simmons CP, Farrar JJ, Nguyen van VC, Wills B. Dengue. N Engl J Med. 2012;366(15):1423–32. doi: 10.1056/NEJMra1110265.

Lam PK, Van Ngoc T, Thu Thuy TT, Hong Van NT, Nhu Thuy TT, Hoai Tam DT, et al. The value of daily platelet counts for predicting

dengue shock syndrome: Results from a prospective observational study of 2301 Vietnamese children with dengue. PLoS Negl Trop Dis.

;11(4):e0005498. doi: 10.1371/journal.pntd.0005498.

Rhodes A, Evans LE, Alhazzani W, Levy MM, Antonelli M, Ferrer R, et al. Surviving sepsis campaign: International guidelines for

management of sepsis and Septic Shock: 2016. Intensive Care Med. 2017;43(3):304–77. doi: 10.1007/s00134-017-4683-6.

Shrestha GS, Kwizera A, Lundeg G, Baelani JI, Azevedo LCP, Pattnaik R, et al. International Surviving Sepsis Campaign guidelines 2016: the perspective from low-income and middle-income countries. Lancet Infect Dis. 2017;17(9):893–5. doi: 10.1016/S1473-3099(17)30453-X.

Rajapakse S, de Silva NL, Weeratunga P, Rodrigo C, Fernando SD. Prophylactic and therapeutic interventions for bleeding in dengue: a systematic review. Trans R Soc Trop Med Hyg. 2017;111(10):433–9. doi: 10.1093/trstmh/trx079.

Díaz-Quijano FA, Villar-Centeno LA, Martínez-Vega RA. Effectiveness of early dipyrone administration on severity of dengue virus

infection in a prospective cohort. Enferm Infecc Microbiol Clin. 2005;23(10):593–7. doi: 10.1157/13081567.

Thein T-L, Lye DC, Leo Y-S, Wong JGX, Hao Y, Wilder-Smith A. Severe neutropenia in dengue patients: prevalence and significance.

Am J Trop Med Hyg. 2014;90(6):984–7. doi: 10.4269/ajtmh.14-0004.

Byard RW. Lethal dengue virus infection: A forensic overview. Am J Forensic Med Pathol. 2016;37(2):74–8. doi: 10.1097/

PAF.0000000000000236.

Published

2023-03-31

Issue

Section

Brief Report

How to Cite

1.
Luque N, Cilloniz C, Pons MJ, Donaires F, Albornoz R, Mendocilla-Risco M, et al. Clinical-epidemiological characteristics of dengue deaths during an outbreak in northern Peru. Rev Peru Med Exp Salud Publica [Internet]. 2023 Mar. 31 [cited 2024 Jun. 23];40(1):67-72. Available from: https://rpmesp.ins.gob.pe/index.php/rpmesp/article/view/12148

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