Effect of sacha inchi oil (Plukenetia volúbilis L) on the lipid profile of patients with hyperlipoproteinemia

Authors

  • Fausto Garmendia Instituto de Investigaciones Clínicas, Universidad Nacional Mayor de San Marcos. Lima, Perú. Academia Nacional de Medicina. Lima, Perú. Médico, Doctor en Medicina.
  • Rosa Pando Instituto de Investigaciones Clínicas, Universidad Nacional Mayor de San Marcos. Lima, Perú. Hospital Nacional Dos de Mayo. Lima, Perú. Médico Cirujano.
  • Gerardo Ronceros Instituto de Investigaciones Clínicas, Universidad Nacional Mayor de San Marcos. Lima, Perú. Hospital Nacional Dos de Mayo. Lima, Perú. Médico, Magister en Bioquímica.

DOI:

https://doi.org/10.17843/rpmesp.2011.284.426

Keywords:

Hyperlipoproteinemias, Hypercholesterolemia, Plukenetia volubilis L.

Abstract

We performed a pilot, experimental, open study in order to know the effect, effective dosage and secondary effects of sacha inchi´s (Plukenetia volúbilis L) oil on the lipid profiles of patients with hypercholesterolemia. We included 24 patients of ages 35 to 75, to whom we measured total cholesterol (TC), HDL, triglycerides (Tg), glucose (G), non-esterified fatty acids (NEFA) and insulin (I) levels in blood, then we randomized them to receive sacha inchi oil orally 5 ml or 10 ml of a suspension of sacha inchi oil (2gr/5ml) for four months. The oil intake produced a decrease in the mean values of TC, and NEFA, and a rise in HDL in both subgroups. The subgroup receiving 10 ml was associated to an increase in the insulin levels. Sacha inchi oil appears to have beneficial effects on the lipid profile of patients with dyslipidemia, but their efficacy and security should be evaluated in randomized clinical trials.

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Published

2014-01-29

How to Cite

1.
Garmendia F, Pando R, Ronceros G. Effect of sacha inchi oil (Plukenetia volúbilis L) on the lipid profile of patients with hyperlipoproteinemia. Rev Peru Med Exp Salud Publica [Internet]. 2014 Jan. 29 [cited 2024 May 25];28(4). Available from: https://rpmesp.ins.gob.pe/index.php/rpmesp/article/view/426

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