Frecuencia y factores asociados a la  preferencia de autotoma para detección del virus del papiloma humano

María A.  Rosas-Mendoza; Yuly R. Santos-Rosales; Marco A.  Chilipio-Chiclla

doi:10.17843/rpmesp.2025.422.14372

Authors

María A. Rosas-Mendoza Universidad Nacional Mayor de San Marcos, Facultad de Medicina, Lima, Perú https://orcid.org/0009-0007-6952-408X
Yuly R. Santos-Rosales Universidad Nacional Mayor de San Marcos, Facultad de Medicina, Lima, Perú. Hospital San Juan de Lurigancho, Lima, Perú https://orcid.org/0000-0002-4536-8293
Marco A. Chilipio-Chiclla Universidad Nacional Mayor de San Marcos, Facultad de Medicina, Lima, Perú https://orcid.org/0000-0001-6076-8634

DOI:

https://doi.org/10.17843/rpmesp.2025.422.14372

Keywords:

Human Papillomavirus DNA Tests, Human Papillomavirus Viruses, Mass Screening, Self-administration

Abstract

Objective. To analyze the frequency and factors associated with self-sampling preference for detecting human papillomavirus (HPV) in Peruvian women at a healthcare center, 2023-2024. Materials and methods. A cross-sectional analytical study was conducted. The sample consisted of 275 women aged 30 to 49 years who
from the Rinconada Healthcare Center. The main variable was evaluated directly using a dichotomous question, which revealed the user’s preference for this method of cervical sample collection for HPV detection. The instrument was a valid and reliable questionnaire. Multivariate statistics were used to find the associated factors. Results. We found that 75.6% of users prefer self-sampling for HPV detection. Adjusted analysis showed that higher education (RPa=1.28; 95% CI: 1.01-1.64) and secondary education (RPa=1.46; 95% CI: 1.11-1.92) increased the likelihood of preferring self-sampling; while cohabiting marital status (RPa=0.61; 95% CI: 0.44-0.83), being from the rest of the coast (RPa=0.70; 95% CI: 0.50-0.97), Catholic religion (RPa=0.84; 95% CI: 0.74-0.96) and having a higher quartile of knowledge about HPV (RPa=0.88; 95% CI: 0.71-0.95) reduced the likelihood of preferring self-sampling. Conclusion. The frequency of preference for self-sampling for HPV detection is high and is associated with secondary/higher education, cohabitation, living on the coast except for the capital, being Catholic, and having a higher level of knowledge about HPV.

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References

Organización Mundial de la Salud [Internet]. Cáncer cérvicouterino. Washington D.C: OMS:; 2018 [consultado el 16 de febrero del 2023]. Disponible en: https://www.paho.org/es/temas/cancer-cervicouterino.

Organización Mundial de la Salud [Internet]. Cancer today. Washington D.C: OMS:; 2022 [consultado el 16 de febrero del 2023].

Disponible en: https://gco.iarc.fr/today/data/factsheets/populations/604-peru-fact-sheets.pdf.

Ministerio de Salud. Guía de práctica clínica para la prevención y manejo del cáncer de cuello uterino. Guía técnica [Internet]. Lima:

Dirección General de Intervenciones Estratégicas en Salud Pública, MINSA; 2017. [consultado el 16 de febrer de 2023]. Disponible en:

https://cdn.www.gob.pe/uploads/document/file/342285/Gu%C3%ADa_de_pr%C3%A1ctica_cl%C3%ADnica_para_la_prevenci%C3%B-

n_y_manejo_del_c%C3%A1ncer_de_cuello_uterino._Gu%C3%ADa_t%C3%A9cnica20190716-19467.

Calderón K, Patazca J, Soto V. Factores que intervienen en la decisión de la toma de la prueba de papanicolaou en mujeres de 20 a 69 años del distrito de Lambayeque. Rev Exp Med. 2018; 4(2): 51-55. Disponible en: https://rem.hrlamb.gob.pe/index.php/REM/article/view/206.

Aldave A, Apolaya M. Factores asociados al incumplimiento del despistaje oportuno con papanicolaou en la detección temprana del cáncer de cérvix en un centro poblado rural. Acta Méd Peruana. 2019; 36(4): 359-266. doi: 10.35663/amp.2019.364.899.

Rivera M. Tamizaje de cáncer cervicouterino en Chile: ¿Pap o VPHtest? Una revisión de literatura. Rev Conflu. 2021; 4(1): 98-103. doi:

52611/confluencia.num1.2021.556.

Fonseca C. Autotoma de células cervicales con identificación del DNA del virus del papiloma humano, una alternativa en la política pública de tamización de cáncer de cérvix para poblaciones rurales en Colombia. Cienc Lat. 2022; 6(3): 1157-1167. doi: 10.37811/cl_rcm.v6i3.2280.

Cabrera S, Linares A, Martínez J, Abullarade J. Autotoma para detección de VPH comparada con muestra convencional en el tamizaje de cáncer cervicouterino. Alerta. 2022; 5(1): 81-87. doi: 10.5377/alerta.v5i1.12806.

Serrano B, Ibáñez R, Peremiquel P, De Sanjosé S, Bruni L. Worldwide use of HPV self-sampling for cervical cancer screening. Prev Med.

; 154: e106900. doi: 10.1016/j.ypmed.2021.106900.

Léniz J, Barriga M, Lagos M, Ibáñez C, Puschel K, Ferrecio K. HPV vaginal self-sampling among women non-adherent to Papanicolaou

screening in Chile. Salud Públ Mex. 2013; 55(2): 162-169. Disponible en: https://www.scielo.org.mx/pdf/spm/v55n2/v55n2a07.pdf.

Gottschlich A, Rivera A, Grajeda E, Alvarez C, Mendoza C, Meza R. Acceptability of Human Papillomavirus Self-Sampling for Cervical

Cancer Screening in an Indigenous Community in Guatemala. J Glob Oncol. 2017; 3(5): 444-454. doi: 10.1200/JGO.2016.005629.

Marlow L, Zimet G, McCaffery K, Ostini R, Waller J. Knowledge of human papillomavirus (HPV) and HPV vaccination: An international comparison. Vaccine. 2013; 31(5): 763-769. doi: 10.1016/j.vaccine.2012.11.083.

Hosmer D, Lemeshow S. Model-building strategies and methods for logistic regression. In Hosmer D, Lemeshow S. Applied kogistic

regresion. 2nd ed. New York: Wiley; 2000. p.91-142. Disponible en: https://onlinelibrary.wiley.com/doi/abs/10.1002/0471722146.ch4.

Oneko O, Mahande M, Amour C, Pollie M, Smith C, Mboya I, et al. Willingness to HPV self-sampling for cervical cancer screening and

its predictors among women attending outpatient clinics in Meru District, Arusha Region, Northern Tanzania. Afr Health Sci. 2022;

(2): 97-106. doi: 10.4314/ahs.v22i2.12.

Chaw L, Lee S, Hazwani N, Lim E, Sharbawi R. Reasons for non-attendance to cervical cancer screening and acceptability of HPV

self-sampling among Bruneian women: A cross-sectional study. PLoS One. 2022; 17(3): e0262213. doi: 10.1371/journal.pone.0262213.

Faradisa E, Ardiana H, Priyantini D, Fauziah A, Susanti I. A Systematic Review of the Factors Associated with Cervical Cancer Screening

Uptake among Women in Low and Middle-Income Countries. Jurnal NERS. 2020; 15(1): 113-119. doi: 10.20473/jn.v15i1Sp.18991.

Sormani J, Kenfack B, Wisniak A, Datchoua A, Makajio S, Schmidt N, et al. Exploring Factors Associated with Patients Who Prefer

Clinician-Sampling to HPV Self-Sampling: A Study Conducted in a Low-Resource Setting. Int J Environ Res Public Health. 2021; 19(1): 54. doi: 10.3390/ijerph19010054.

Besó M, Ibáñez J, Molina A, Zurriaga O, Salas D. ¿Aceptan las mujeres de la Comunidad Valenciana la auto-toma como forma de cribado de cáncer de cérvix? Rev Esp Salud Pública. 2021; 95(26): e1-e18. Disponible en: https://dialnet.unirioja.es/servlet/articulo?codigo=7957684.

Ma’som M, Bhoo N, Hairizan N, Bellison J, Subramaniam S, Ma Y, et al. Attitudes and factors affecting acceptability of self-administered cervicovaginal sampling for human papillomavirus (HPV) genotyping as an alternative to Pap testing among multiethnic Malaysian women. BMJ Open. 2016; 6(8): e011022. doi: 10.1136/bmjopen-2015-011022.

Wong E, Cheung A, Huang F, Chor J. Can Human Papillomavirus DNA Self-sampling be an Acceptable and Reliable Option for Cervical

Cancer Screening in Female Sex Workers? Cancer Nurs. 2018; 41(1): 45-52. doi: 10.1097/NCC.0000000000000462.

Adegboyega A, Wiggins A, Williams L, Dignan M. HPV Testing Behaviors and Willingness to Use HPV Self-sampling at Home Among

African American (AA) and Sub-Saharan African Immigrant (SAI) Women. J Racial Ethn Health Disparities. 2022; 9(6): 2485-2494. doi: 10.1007/s40615-021-01184-4.

Gonzáles M, Aguilar M, Gonzáles L. Creencias tradicionales mexicanas y su relación con la aceptación de la autotoma vaginal para la detección del VPH. Ginecol Obstet Méx. 2022; 90(3): 207-213. doi: 10.24245/gom.v90i3.5849.

Nishimura H, Yeh P, Oguntade H, Kennedy C, Narasimhan M. HPV self-sampling for cervical cancer screening: a systematic review ofvalues and preferences. BMJ Glob Health. 2021; 6(5): e003743. doi: 10.1136/bmjgh-2020-003743.

Khoo S, Lim W, Rajasuriar R, Nasir N, Gravitt P, Woo Y. The Acceptability and Preference of Vaginal Self-sampling for Human Papillomavirus (HPV) Testing among a Multi-ethnic Asian Female Population. Cancer Prev Res (Phila). 2021; 14(1): 105-112. doi: 10.1158/1940-6207.CAPR-20-0280.

Sormani J, Kenfack B, Wisniak A, Datchoua A, Makajio S, Schmidt N, et al. Exploring Factors Associated with Patients Who Prefer Clinician-Sampling to HPV Self-Sampling: A Study Conducted in a Low-Resource Setting. Int J Environ Res Public Health. 2021; 19(1): e54. doi: 10.3390/ijerph19010054.