Demographic characteristics of human papillomavirus detected by PCR-RFLP in peruvian women
Keywords:Human papilloma virus, Genotype, Polymerase chain reaction
AbstractIn order to determine the sociodemographic characteristics of human papillomavirus (HPV) in patients referred to the National Institute of Neoplastic Diseases (INEN) between 2012-2014, the detection of HPV in cervical cells was performed by polymerase chain reaction (PCR). In 465 cervical samples, 151 (32.5%) cases were HPV positive. The most common genotypes were HPV-16 (23.8%) and HPV-6 (11.9%). The presence of HPV was higher in women aged 17-29 years (OR = 2.64, 95% CI 1.14 to 6.13) and single women (OR = 2.31, 95% CI 1.37 to 3.91). The presence of genotypes of high-risk HPV was higher in single women (OR = 2.19, 95% CI 1.04 to 4.62). In conclusion, young and single women had a higher frequency of HPV-positive cases. Therefore participation by these groups should be emphasized in screening programs with combined molecular and cytological methods in order to detect the risk of developing cervical cancer in a timely manner.
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Sullcahuaman-Allende Y, Castro-Mujica M del C, Mejía Farro R, Castañeda CA, Castillo M, Dolores-Cerna K, Poquioma E. Demographic characteristics of human papillomavirus detected by PCR-RFLP in peruvian women. Rev Peru Med Exp Salud Publica [nternet]. 2015 Sep. 24 [cited 2023 Jun. 4];32(3):509-14. vailable from: https://rpmesp.ins.gob.pe/index.php/rpmesp/article/view/1684