Prevalence of hepatitis B infection in children under 5 years old on indigenous communities of the peruvian amazonia after immunization interventions

Authors

  • César Cabezas-Sánchez Centro Nacional de Salud Pública, Instituto Nacional de Salud. Lima, Perú. Instituto de Medicina Tropical “Daniel A. Carrión”, Universidad Nacional Mayor de San Marcos. Lima, Perú. Médico infectólogo.
  • Omar Trujillo-Villarroel Centro Nacional de Salud Intercultural, Instituto Nacional de Salud. Lima, Perú. Médico epidemiólogo.
  • Carol Zavaleta-Cortijo Centro Nacional de Salud Intercultural, Instituto Nacional de Salud. Lima, Perú. Médico cirujano.
  • Dante Culqui-Lévano Centro Nacional de Salud Intercultural, Instituto Nacional de Salud. Lima, Perú. Médico epidemiólogo.
  • Magna Suarez-Jara Centro Nacional de Salud Pública, Instituto Nacional de Salud. Lima, Perú. Biólogo.
  • Neptalí Cueva-Maza Centro Nacional de Salud Intercultural, Instituto Nacional de Salud. Lima, Perú. Médico cirujano.
  • Shirley Monzon Centro Nacional de Salud Intercultural, Instituto Nacional de Salud. Lima, Perú. Médico cirujano.

DOI:

https://doi.org/10.17843/rpmesp.2014.312.36

Keywords:

Hepatitis B, Immunization, Child, Indigenous population, Seroprevalence

Abstract

Objectives. To determine the prevalence of hepatitis B virus (HVB) infection and seroprotection in indigenous children living in three draining basins of the Peruvian Amazon. Materials and methods. A cross sectional study was conducted in three draining basins (Pastaza, Morona and Lower Urubamba rivers), home to six indigenous populations: shapra, candoshi, machiguenga, yine, ashaninka and nanti. Children under 5 years were included. A survey and review of the vaccination card was applied, and a serum sample was processed with ELISA for HBsAg, total anti-HBc and anti-HBs was obtained, defining “seroprotected children” if they were reactive to anti-HBs and non-reactive to anti-HBc. Results. A total of 742 children under 5 years old residents in six indigenous communities were included in the study. 380 (51.2%) were male and 169 (22.9%) one year old or younger. Regarding recorded HVB vaccination on the card, only 434 (58.5%) had received three doses; 208 (38.8%) received the first dose within 24 hours. No cases were detected with HBsAg. 88.8% of children had seroconverted, varying between 67-100% across the populations. Conclusions. No cases of chronic HBV infection were detected. The vaccination coverage by card revision is low, contrasting with high seroconversion rates.

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Published

2014-07-02

Issue

Section

Research Articles

How to Cite

1.
Cabezas-Sánchez C, Trujillo-Villarroel O, Zavaleta-Cortijo C, Culqui-Lévano D, Suarez-Jara M, Cueva-Maza N, et al. Prevalence of hepatitis B infection in children under 5 years old on indigenous communities of the peruvian amazonia after immunization interventions. Rev Peru Med Exp Salud Publica [Internet]. 2014 Jul. 2 [cited 2024 May 29];31(2). Available from: https://rpmesp.ins.gob.pe/index.php/rpmesp/article/view/36