Prevalence of hepatitis B infection in children under 5 years old on indigenous communities of the peruvian amazonia after immunization interventions
Keywords:Hepatitis B, Immunization, Child, Indigenous population, Seroprevalence
AbstractObjectives. To determine the prevalence of hepatitis B virus (HVB) infection and seroprotection in indigenous children living in three draining basins of the Peruvian Amazon. Materials and methods. A cross sectional study was conducted in three draining basins (Pastaza, Morona and Lower Urubamba rivers), home to six indigenous populations: shapra, candoshi, machiguenga, yine, ashaninka and nanti. Children under 5 years were included. A survey and review of the vaccination card was applied, and a serum sample was processed with ELISA for HBsAg, total anti-HBc and anti-HBs was obtained, defining “seroprotected children” if they were reactive to anti-HBs and non-reactive to anti-HBc. Results. A total of 742 children under 5 years old residents in six indigenous communities were included in the study. 380 (51.2%) were male and 169 (22.9%) one year old or younger. Regarding recorded HVB vaccination on the card, only 434 (58.5%) had received three doses; 208 (38.8%) received the first dose within 24 hours. No cases were detected with HBsAg. 88.8% of children had seroconverted, varying between 67-100% across the populations. Conclusions. No cases of chronic HBV infection were detected. The vaccination coverage by card revision is low, contrasting with high seroconversion rates.
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Cabezas-Sánchez C, Trujillo-Villarroel O, Zavaleta-Cortijo C, Culqui-Lévano D, Suarez-Jara M, Cueva-Maza N, Monzon S. Prevalence of hepatitis B infection in children under 5 years old on indigenous communities of the peruvian amazonia after immunization interventions. Rev Peru Med Exp Salud Publica [nternet]. 2014 Jul. 2 [cited 2023 Jun. 1];31(2). vailable from: https://rpmesp.ins.gob.pe/index.php/rpmesp/article/view/36
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