Implementation of a telediagnostic system for tuberculosis and determination of multi-drug resistance based in the MODS method in Trujillo, Peru

Authors

  • Luis Rodríguez Centro de Excelencia en Tuberculosis “Luz Caviedes Rojas”, Hospital Regional Docente de Trujillo. La Libertad, Perú. Facultad de Medicina Universidad Nacional de Trujillo. La Libertad, Perú. Médico internista, neumólogo
  • Alicia Alva Laboratorio de Investigación en Enfermedades Infecciosas, Laboratorio de Investigación y Desarrollo. Facultad de Ciencias y Filosofía. Universidad Peruana Cayetano Heredia. Lima, Perú Bachiller en Matemática Pura
  • Jorge Coronel Laboratorio de Investigación en Enfermedades Infecciosas, Laboratorio de Investigación y Desarrollo. Facultad de Ciencias y Filosofía. Universidad Peruana Cayetano Heredia. Lima, Perú. tecnólogo médico
  • Luz Caviedes Laboratorio de Investigación en Enfermedades Infecciosas, Laboratorio de Investigación y Desarrollo. Facultad de Ciencias y Filosofía. Universidad Peruana Cayetano Heredia. Lima, Perú. bióloga
  • Alberto Mendoza-Ticona Instituto Nacional de Salud. Lima, Perú. médico infectólogo
  • Robert Gilman ONG A.B. PRISMA. Lima, Perú. médico
  • Patricia Sheen Laboratorio de Investigación en Enfermedades Infecciosas, Laboratorio de Investigación y Desarrollo. Facultad de Ciencias y Filosofía. Universidad Peruana Cayetano Heredia. Lima, Perú. bióloga
  • Mirko Zimic Laboratorio de Investigación en Enfermedades Infecciosas, Laboratorio de Investigación y Desarrollo. Facultad de Ciencias y Filosofía. Universidad Peruana Cayetano Heredia. Lima, Perú. físico

DOI:

https://doi.org/10.17843/rpmesp.2014.313.79

Keywords:

Multiple organ failure, Mycobacterium tuberculosis, Tuberculosis, multidrug-resistant

Abstract

Objectives. To implement a system for remote diagnosis of tuberculosis and multidrug resistance (MDR) using the Microscopic-Observation Drug Susceptibility Assay (MODS) method in the Mycobacteria Laboratory, Trujillo Center of Excellence in Tuberculosis (CENEX-Trujillo). The system included a variant of an algorithm for recognition of Mycobacterium tuberculosis recently reported from digital images of MODS cultures of sputum samples. Materials and methods. The recognition algorithm was optimized using a retraining statistical model based on digital images of MODS cultures from CENEX-Trujillo. Images of 50 positive MODS cultures of patients with suspected multidrug-resistant tuberculosis were obtained between January and October 2012 in the CENEX-Trujillo. Results. The sensitivity and specificity to recognize strings of tuberculosis were 92.04% and 94.93% respectively using objects. The sensitivity and specificity to determine a positive tuberculosis field were 95.4% and 98.07% respectively using pictures. Conclusions. The results demonstrated the feasibility of the implementation of telediagnostics in remote locations, which may contribute to the early detection of multidrug-resistant tuberculosis by MODS method.

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Published

2014-09-25

Issue

Section

Research Articles

How to Cite

1.
Rodríguez L, Alva A, Coronel J, Caviedes L, Mendoza-Ticona A, Gilman R, et al. Implementation of a telediagnostic system for tuberculosis and determination of multi-drug resistance based in the MODS method in Trujillo, Peru. Rev Peru Med Exp Salud Publica [Internet]. 2014 Sep. 25 [cited 2024 Jun. 23];31(3). Available from: https://rpmesp.ins.gob.pe/index.php/rpmesp/article/view/79

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