Factors associated with the use of psychotropic drugs by students at a Brazilian public university

Authors

DOI:

https://doi.org/10.17843/rpmesp.2024.414.13858

Keywords:

Medications, Psychotropic Drugs, Student Health, University, Brazil

Abstract

Objective. To analyze the consumption of psychotropic drugs and their associated factors in university students, stratified by sex. Materials and methods. We conducted a cross-sectional study with undergraduate students of a public university in Brazil. The instrument was an online self-administered questionnaire. The outcome variable was the use of psychotropic drugs, based on the Anatomical Therapeutic Chemical (ATC) classification system, and the exposure variables were socio-demographic, academic and health-related. The association between the exposure variables and the outcome was verified by calculating prevalence ratios and their 95% confidence intervals. Results. We found that 12.2% (n=396) of the 3238 participants used psychotropic drugs; most were women (78.3%). The prevalence of psychotropic drug use was higher among students with access to health insurance, diagnosis of depression and diagnosis of anxiety. It was also higher in the group of women who reported using illicit drugs in the last three months and in the group of men who reported being dissatisfied or very dissatisfied with their academic performance. We detected low frequency of psychotropic drug use among women who consume
alcohol on a weekly basis. Conclusions. Our results show a higher frequency of psychotropic medication use in females, as well as in students with access to health insurance, diagnosis of depression and diagnosis of
anxiety, regardless of sex.

 

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References

Nogueira MJ, Seabra P, Alves P, Teixeira D, Carvalho JC, Sequeira C. Predictors of positive mental health in higher education students.

A cross-sectional predictive study. Perspect Psychiatr Care. 2022;58(4):2942–9. doi: 10.1111/ppc.13145.

Castaldelli-Maia JM, Lewis T, Marques dos Santos N, Picon F, Kadhum M, Farrell SM, et al. Stressors, psychological distress, and mental health problems amongst Brazilian medical students. Int Rev Psychiatry. 2019;31(7–8):603–7. doi: 10.1080/09540261.2019.1669335.

Sheldon E, Simmonds-Buckley M, Bone C, Mascarenhas T, Chan N, Wincott M, et al. Prevalence and risk factors for mental health

problems in university undergraduate students: A systematic review with meta-analysis. J Affect Disord. 2021;287:282–92. doi:

1016/j.jad.2021.03.054.

Beroíza-Valenzuela F. The challenges of mental health in Chilean university students. Front Public Heal. 2024;12:1297402. doi:

3389/fpubh.2024.1297402.

Lima AMS, Leal R, Fernandes dos Santos V, Leal L, Rocha A, Silva E, et al. Prevalência da Depressão nos Acadêmicos da Área de Saúde. Psicol Ciênc Prof. 2019;39:e187530. doi: 10.1590/1982-3703003187530.

Pacheco JPG, Giacomin HT, Tam WW, Ribeiro TB, Arab C, Bezerra IM, et al. Mental health problems among medical students in

Brazil: a systematic review and meta-analysis. Rev Bras Psiquiatr. 2017;39(4):369–78. doi: 10.1590/1516-4446-2017-2223.

Bojanić I, Sund ER, Bjerkeset O, Sivertsen B, Sletvold H. Psychological Distress and Use of Psychotropic Drugs Among University

Students—the SHoT Study, Norway. Front Psychiatry. 2021;12717955. doi: 10.3389/fpsyt.2021.717955.

Fond G, Bourbon A, Boucekine M, Messiaen M, Barrow V, Auquier P, et al. First-year French medical students consume antidepressants and anxiolytics while second-years consume non-medical drugs. J Affect Disord. 2020;265:71–6. doi: 10.1016/j.jad.2020.01.035.

Sobral de Luna I, Augusta Grigoli Dominato A, Ferrari F, Lobo da Costa A, Christhinie Pires A, da Silva Ximendes G. Consumo de psicofármacos entre alunos de medicina do primeiro e sexto ano de uma universidade do estado de São Paulo. Colloq Vitae. 2018;10(1):22–8. doi: 10.5747/cv.2018.v10.n1.v216.

Fasanella NA, Custódio CG, Cabo JS, Andrade GS, Almeida FA, Pavan MV. Use of prescribed psychotropic drugs among medical students and associated factors: a cross-sectional study. Sao Paulo Med J. 2022;140(5):697–704. doi: 10.1590/1516-3180.2021.0566.R2.05012022.

Scheifes A, Walraven S, Stolker JJ, Nijman HLI, Egberts TCG, Heerdink ER. Adverse events and the relation with quality of life in adults with intellectual disability and challenging behaviour using psychotropic drugs. Res Dev Disabil. 2016;49–50:13–21. doi: 10.1016/j.ridd.2015.11.017.

SenthilKumar G, Mathieu NM, Freed JK, Sigmund CD, Gutterman DD. Addressing the decline in graduate students’ mental well-being.

Am J Physiol - Hear Circ Physiol. 2023;325(4):H882–7. doi: 10.1152/ajpheart.00466.2023.

Bacigalupe A, Martín U. Gender inequalities in depression/anxiety and the consumption of psychotropic drugs: are we medicalising

women’s mental health? Scand J Public Health. 2021;49(3):317–24. doi: 10.1177/1403494820944736.

Quintana MI, Andreoli SB, Peluffo MP, Ribeiro WS, Feijo MM, Bressan RA, et al. Psychotropic drug use in São Paulo, Brazil: an epidemiological survey. PLoS One. 2015; 10(8):e0135059. doi: 10.1371/journal.pone.0135059.

Von Elm E, Altman DG, Egger M, Pocock SJ, Gøtzsche PC, Vandenbroucke JP, et al. Strengthening the reporting of observational

studies in epidemiology (StroBE) statement: guidelines for reporting observational studies. Ann Intern Med. 2007;147(8):573–7. doi:

7326/0003-4819-147-8-200710160-00010.

Frazon AG. Síndrome de burnout e o consumo de álcool e de substâncias ilícitas por estudantes universitários [Tese]. Londrina: Universidade Estadual de Londrina; 2021. 184 p.

World Health Organization. ATC/DDD Index 2022. Geneva: OMS; 2022. [cited 2023 Sept 21]. Available from: https://www.whocc.no/atc_ddd_index/.

Liu Y, Zhang N, Bao G, Huang Y, Ji B, Wu Y, et al. Predictors of depressive symptoms in college students: A systematic review and

meta-analysis of cohort studies. J Affect Disord. 2019;244:196–208. doi: 10.1016/j.jad.2018.10.084.

Bacigalupe A, Martín U. Gender inequalities in depression/anxiety and the consumption of psychotropic drugs: Are we medicalising

women’s mental health? Scand J Public Health. 2021;49(3):317-324. doi: 10.1177/1403494820944736.

Santos LH, Silveira MM. Uso de psicofármacos por estudantes de psicologia. Cad Bras Saúde Mental. 2019;11(29):1–12. doi: 10.5007/cbsm.v11i29.69801.

Câmara H, Rocha C, Balteiro J. Grau de conhecimento e consumo de psicofármacos dos alunos da Escola Superior de Tecnologia da

Saúde de Coimbra. Rev Port Saude Publica. 2011;29(2):173–9. doi: 10.1016/S0870-9025(11)70021-9.

Berchtold A, Genre N, Panese F. Uses of psychotropic drugs by university students in Switzerland. PLoS One. 2024;19(6):e0305392. doi: 10.1371/journal.pone.0305392

Marchi KC, Bárbaro AM, Miasso AI, Tirapelli CR. Ansiedade e consumo de ansiolíticos entre estudantes de enfermagem de uma universidade pública. Rev Eletr Enf. 2013;15(3):731–9. doi: 10.5216/ree.v15i3.18924.

Istilli PT, Miasso AI, Padovan CM, Crippa JA, Tirapelli CR. Antidepressants: knowledge and use among nursing students. Rev Lat-Am

Enfermagem. 2010;18(3):421–8. doi: 10.1590/S0104-11692010000300018.

Souza GCRM, Vasques JS, Rodrigues LAC, Komatsu AV, Silva JL, Maniglia FP. Uso de ansiolíticos e antidepressivos entre estudantes

de medicina de uma universidade. Psico. 2022;53(1):e38105. doi: 10.15448/1980-8623.2022.1.38105.

Bielli A, Bacci P, Bruno G, Calisto N. Cambiar para que todo siga igual: mujeres y psicofármacos en Uruguay. Rev Estud Fem. 2023;31(1): e93197. doi: 10.1590/1806-9584-2023v31n193197.

Lun KWC, Chan CK, Ip PKY, Ma SYK, Tsai WW, Wong CS, et al. Depression and anxiety among university students in Hong Kong. Hong Kong Med J. 2018;24(5):466–72. doi: 10.12809/hkmj176915.

Parker G, Brotchie H. Gender differences in depression. Int Rev Psychiatry. 2010;22(5):429–36. doi: 10.3109/09540261.2010.492391.

Ribeiro AG, da Cruz LP, Marchi KC, Tirapelli CR, Miasso AI. Antidepressivos: uso, adesão e conhecimento entre estudantes de medicina. Ciênc Saude Coletiva. 2014;19(6):1825–33. doi: 10.1590/1413-81232014196.06332013.

Assem-Hilger E, Jungwirth S, Weissgram S, Kirchmeyr W, Fischer P, Barnas C. Benzodiazepine use in the elderly: An indicator for

inappropriately treated geriatric depression? Int J Geriatr Psychiatry. 2009;24(6):563–9. doi: 10.1002/gps.2155

Szwarcwald CL, Stopa SR, Damacena GN, Almeida WS, Souza Júnior PRB, Vieira MLFP, et al. Changes in the pattern of health services use in brazil between 2013 and 2019bl health journal. Ciênc Saude Coletiva. 2021;26(suppl1):2515–28. doi: 10.1590/1413-81232021266.1.43482020.

Berrouet Mejía MC, Lince Restrepo M, Restrepo Bernal D. Actitudes, conocimientos y prácticas frente a la automedicación con productos herbales y psicofármacos en estudiantes de medicina de Medellín-Colombia. Med UPB. 2018;37(1):17–24. doi: 10.18566/medupb.v37n1.a03.

Telles Filho PCP, Pereira Júnior AC. Antidepressivos: Consumo, Orientação E Conhecimento Entre Acadêmicos De Enfermagem. Rev Enferm Cent O Min. 2013;3(3):829–36. doi: 10.19175/recom.v0i0.411.

Martins de Oliveira L, Pereira de Menezes Filho AC, Porfiro CA. Uso da Passiflora incarnata L. no tratamento alternativo do transtorno de ansiedade generalizada. Res Soc Dev. 2020;9(11):e2349119487. doi: 10.33448/rsd-v9i11.9487.

Abi-Ackel MM, Lima-Costa MF, Castro-Costa E, Loyola Filho AI. Uso de psicofármacos entre idosos residentes em comunidade: prevalência e fatores associados. Rev Bras Epidemiol. 2017;20(1):57–69. doi: 10.1590/1980-5497201700010005.

Deus MD, Schmitz MES, Vieira ML. Família, gênero e jornada de trabalho: uma revisão sistemática de literatura. Gerais, Rev Interinst Psicol. 2021;14(1):1–28. doi: 10.36298/gerais202114e15805.

Campo-Arias A, Suárez-Colorado YP, Caballero-Domínguez CC. Asociación entre el consumo de Cannabis y el riesgo de suicidio en adolescentes escolarizados de Santa Marta, Colombia. Biomed. 2020;40(3):569–77. doi: 10.7705/biomedica.4988.

Rotenstein LS, Ramos MA, Torre M, Bradley Segal J, Peluso MJ, Guille C, et al. Prevalence of depression, depressive symptoms, and suicidal ideation among medical students a systematic review and meta-analysis. JAMA. 2016;316(21):2214–36. doi: 10.1001/jama.2016.17324.

Candido FJ, Souza R, Stumpf MA, Fernandes LG, Veiga R, Santin M, et al. The use of drugs and medical students: A literature review. Rev Assoc Med Bras. 2018;64(5):462–8. doi: 10.1590/1806-9282.64.05.462.

Rabiee R, Lundin A, Agardh E, Hensing G, Allebeck P, Danielsson AK. Cannabis use and the risk of anxiety and depression in women: A comparison of three Swedish cohorts. Drug Alcohol Depend. 2020;216:108332. doi: 10.1016/j.drugalcdep.2020.108332.

Tovani JBE, Santi LJ, Trindade EV. Use of psychotropic drugs by students from the health area: a comparative and qualitative analysis. Rev Bras Educ Med. 2021;45(3):1–10. doi: 10.1590/1981-5271v45.3-20200485.ING.

Wang K, Liu Y, Ouedraogo Y, Wang N, Xie X, Xu C, et al. Principal component analysis of early alcohol, drug and tobacco use with major depressive disorder in US adults. J Psychiatr Res. 2018;100:113–20. doi: 10.1016/j.jpsychires.2018.02.022.

Amin-Esmaeili M, Rahimi-Movaghar A, Sharifi V, Hajebi A, Radgoodarzi R, Mojtabai R, et al. Epidemiology of illicit drug use disorders in Iran: prevalence, correlates, comorbidity and service utilization results from the Iranian Mental Health Survey. Addiction. 2016;111(10):1836–47. doi: 10.1111/add.13453.

Raposo JCDS, Costa ACQ, Valença PAM, Zarzar PM, Diniz AS, Colares V, et al. Binge drinking and illicit drug use among adolescent students. Rev Saude Publica. 2017;51:83. doi: 10.11606/S1518-8787.2017051006863.

Bhatti AB, Haq AU. The pathophysiology of perceived social isolation: effects on health and mortality. Cureus. 2017;9(1):e994. doi:

7759/cureus.994.

Gémes K, Forsell Y, Janszky I, László KD, Lundin A, Ponce De Leon A, et al. Moderate alcohol consumption and depression – a longitudinal population-based study in Sweden. Acta Psychiatr Scand. 2019;139(6):526–35. doi: 10.1111/acps.13034.

Wium-Andersen MK, Ørsted DD, Tolstrup JS, Nordestgaard BG. Increased alcohol consumption as a cause of alcoholism, without similar evidence for depression: a Mendelian randomization study. Int J Epidemiol. 2015;44(2):526–39. doi: 10.1093/ije/dyu220.

Blumenberg C, Barros AJD. Response rate differences between web and alternative data collection methods for public health research: a systematic review of the literature. Int J Public Health. 2018;63(6):765–73. doi: 10.1007/s00038-018-1108-4.

Bispo Júnior JP. Social desirability bias in qualitative health research. Rev Saude Publica. 2022;56:101. doi: 10.11606/s1518-8787.2022056004164.

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Published

2024-11-25

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How to Cite

1.
Fares Gianjacomo TR, Molino Guidoni C, Rodrigues R, de Andrade SM, Vertuan Rufino J, Girotto E. Factors associated with the use of psychotropic drugs by students at a Brazilian public university. Rev Peru Med Exp Salud Publica [Internet]. 2024 Nov. 25 [cited 2024 Nov. 26];41(4). Available from: https://rpmesp.ins.gob.pe/index.php/rpmesp/article/view/13858