Reference intervals for peripheral blood lymphocyte subsets in healthy adults in Lima, Peru

Authors

  • José M. Cóndor Instituto de Hemaferesis y Terapia Celular “IHEMATEC”. Lima, Perú. Facultad de Medicina, Universidad Nacional Mayor de San Marcos. Lima, Perú. Tecnólogo médico.
  • Marco Álvarez Instituto de Hemaferesis y Terapia Celular “IHEMATEC”. Lima, Perú. Tecnólogo médico.
  • Luis Cano Instituto de Hemaferesis y Terapia Celular “IHEMATEC”. Lima, Perú. Facultad de Medicina, Universidad Nacional Mayor de San Marcos. Lima, Perú. Tecnólogo médico.
  • Edgar Matos Instituto de Hemaferesis y Terapia Celular “IHEMATEC”. Lima, Perú. médico inmunólogo y alergólogo.
  • Christian Leiva Rochem Biocare. Bogotá, Colombia. Tecnólogo médico.
  • José A. Paredes Facultad de Medicina, Universidad Nacional Mayor de San Marcos. Lima, Perú. Tecnólogo médico. magister en Medicina Transfusional.

DOI:

https://doi.org/10.17843/rpmesp.2013.302.197

Keywords:

Lymphocyte subsets, Flow cytometry, Reference values, Peru

Abstract

In order to establish the reference intervals (RIs) of peripheral blood lymphocyte subsets (PBL) in healthy adults in Lima (Peru), a cross-sectional study was conducted among blood donors taken in between 2011 and 2012. Based on the criteria obtained from the guidelines of the Clinical and Laboratory Standards Institute (CLSI C28-A3), 318 samples were processed, 61.9% (197/318) coming from male donors. For PBL count, a flow cytometer with a simple platform was used. The RIs are established for each PBL in adults based on sex with their respective reference limits and 90% confidence intervals. Differences were found in CD3+ percentage counts (p=0.001) and in CD3-CD56+ absolute (p=0.003) and percentage counts (p˂0.001). The RIs found are different to those described in studies conducted in other countries due to the characteristics of the population and the study model.

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Published

2014-02-10

Issue

Section

Research Articles

How to Cite

1.
Cóndor JM, Álvarez M, Cano L, Matos E, Leiva C, Paredes JA. Reference intervals for peripheral blood lymphocyte subsets in healthy adults in Lima, Peru. Rev Peru Med Exp Salud Publica [Internet]. 2014 Feb. 10 [cited 2024 Mar. 28];30(2). Available from: https://rpmesp.ins.gob.pe/index.php/rpmesp/article/view/197